Results 81 to 90 of about 4,907,732 (327)

Literatura e processos de criação: conversa com Milton Hatoum

Manuscrítica
Conversa entre o escritor manauara Milton Hatoum e a pesquisadora Luz Pinheiro, na Mesa de Artistas do segundo dia do 16º Congresso Internacional da APCG - Arquivo expandido: conexões e processos de criação.  
Milton Hatoum, Luz Pinheiro
doaj   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Mensurando os impactos da abertura econômica sobre o nível de emprego: a contabilidade do crescimento no Brasil entre 1985 e 2000

Economia Aplicada, 2003
In this paper we attempt to analyze the effects of the economic opening observed in Brazil in the early 1990's, on the employment level, compared to the current environment in the 1980's, aiming to test empirically the principles ofthe Theory of ...
Herbert Vieira de Araújo, Francisco Galrão Carneiro   +1 more
doaj  

Fotografia e arquivo: conversa com Eustáquio Neves

Manuscrítica
Conversa entre o fotógrafo mineiro Eustáquio Neves e a pesquisadora Paula Martinelli, na Mesa de Artistas do terceiro dia do 16º Congresso Internacional da APCG - Arquivo expandido: conexões e processos de criação.  
Eustáquio Neves, Paula Martinelli
doaj   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Sem título

Txt: Leituras Transdisciplinares de Telas e Textos, 2016
<em>Sem título</em> por Karol ...
openaire   +4 more sources

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

Sem fronteiras

Análise Social, 2004
Análise Social, Vol. 39 No. 170 (2004)
openaire   +2 more sources

13C-Methyl isocyanide as an NMR probe for cytochrome P450 active site [PDF]

, 2009
The cytochromes P450 (CYPs) play a central role in many biologically important oxidation reactions, including the metabolism of drugs and other xenobiotic compounds.
Im, Sang-Choul, McCullough, Christopher R, Pullela, Phani Kumar, Sem, Daniel S., Waskell, Lucy   +4 more
core   +2 more sources