Results 91 to 100 of about 230,301 (307)

Data Mining Meets Logic: Situation-Based Modal Logic and Metadata Veracity

Science & Philosophy
Logic and theoretical computer science are deeply interconnected, with logic forming a foundational pillar in the emergence of computer science. This connection has grown stronger over time, driven by advancements in symbolic systems within artificial ...
Simone Cuconato
doaj   +1 more source

Toward the Clinical Translation of Implantable Brain–Computer Interfaces for Motor Impairment: Research Trends and Outcome Measures

Advanced Science, EarlyView.
Implantable brain–computer interfaces (iBCIs) are rapidly approaching clinical translation. This review maps key trends in the development of iBCIs and highlights the lack of standardised clinical outcome measures. It discusses a proposed framework for the selection of outcome measures in clinical trials and introduces a new international registry of ...
Esmee Dohle, Eleanor Swanson, Luka Jovanovic, Suraya Yusuf, Lucy Thompson, Hugo Layard Horsfall, William Muirhead, Luke Bashford, Jamie Brannigan   +8 more
wiley   +1 more source

Path querying on acyclic graphs using Boolean grammars

Труды Института системного программирования РАН, 2019
Graph data models are widely used in different areas of computer science such as bioinformatics, graph databases, social networks and static code analysis. One of the problems in graph data analysis is querying for specific paths.
Ekaterina Nikolaevna Shemetova, Semyon Vyatcheslavovitch Grigorev   +1 more
doaj   +1 more source

A Glycoproteome Data Mining Strategy for Characterizing Structural Features of Altered Glycans with Thymic Involution

Advanced Science, EarlyView.
This study presents a comprehensive data mining strategy for in‐depth extraction of overall and altered glycan features from structural and site‐specific glycoproteome data across various biomedical samples. The strategy enables the uncovery of four major altered glycan features associated with thymic involution and reveals their coordinated ...
Zhida Zhang, Yongqi Wu, Ke Hou, Yiwen Zhang, Lin Chen, Muyao Yang, Zhehui Jin, Yongchao Xu, Yingjie Zhang, Yinli Cai, Jiayu Zhao, Shisheng Sun   +11 more
wiley   +1 more source

BInD: Bond and Interaction‐Generating Diffusion Model for Multi‐Objective Structure‐Based Drug Design

Advanced Science, EarlyView.
Can a generative model design molecules that truly understand their targets? BInD, a diffusion‐based framework, co‐generates 3D molecules and their interactions with proteins by learning target‐specific interacting patterns. With knowledge‐based guidance and NCI‐driven optimization, BInD balances affinity, geometry, and drug‐likeness – pushing the ...
Joongwon Lee, Wonho Zhung, Jisu Seo, Woo Youn Kim   +3 more
wiley   +1 more source

An Explainable Multimodal Artificial Intelligence Model Integrating Histopathological Microenvironment and EHR Phenotypes for Germline Genetic Testing in Breast Cancer

Advanced Science, EarlyView.
This study presents an explainable multimodal AI model, MAIGGT (Multimodal Artificial Intelligence Germline Genetic Testing), that combines whole‐slide histopathology with clinical data for accurate germline BRCA1/2 mutation prescreening. By integrating digital pathology and EHR phenotypes, MAIGCT enables cost‐effective, scalable hereditary breast ...
Zijian Yang, Changyuan Guo, Jiayi Li, Yalun Li, Lei Zhong, Pengming Pu, Tongxuan Shang, Lin Cong, Yongxin Zhou, Guangdong Qiao, Ziqi Jia, Hengyi Xu, Heng Cao, Yansong Huang, Tianyi Liu, Jian Liang, Jiang Wu, Dongxu Ma, Yuchen Liu, Ruijie Zhou, Xiang Wang, Jianming Ying, Meng Zhou, Jiaqi Liu   +23 more
wiley   +1 more source

Design and development of semantic web-based system for computer science domain-specific information retrieval

Perspectives in Science, 2016
SummaryIn semantic web-based system, the concept of ontology is used to search results by contextual meaning of input query instead of keyword matching. From the research literature, there seems to be a need for a tool which can provide an easy interface for complex queries in natural language that can retrieve the domain-specific information from the ...
Sonal Chawla, Ritika Bansal
openaire   +2 more sources

Deciphering Cell Type Abundance in Proteomics Data Through Graph Neural Networks

Advanced Science, EarlyView.
GraphDEC constructs pseudo bulk reference data using a mixup strategy, then learns low dimensional representations via autoencoders to model intra and inter dataset relationships. These are processed through a multi view adaptive neighborhood aware GNN, integrating reference, target, and joint graphs.
Zhiming Dai, Yujie Song, Tuoshi Qi, Hongyu Zhang, Huiying Zhao, Zheng Wang, Yuedong Yang, Yuansong Zeng   +7 more
wiley   +1 more source

Meaning and Reference in Programming Languages

Philosophies
This paper provides an analysis of the meaning–reference problem, as traditionally advanced in the philosophy of language, for imperative programming languages.
Nicola Angius
doaj   +1 more source

PlantGPT: An Arabidopsis‐Based Intelligent Agent that Answers Questions about Plant Functional Genomics

Advanced Science, EarlyView.
PlantGPT integrates 60 000+ plant research articles with Arabidopsis phenotype‐gene data through retrieval‐augmented generation and fine‐tuning of Llama3‐8B. This open‐source, specialized AI system outperforms general large language models in plant gene‐phenotype relationships, establishing a new paradigm for functional genomics research and molecular ...
Ruixiang Zhang, Yu Wang, Weiyang Yang, Jun Wen, Weizhi Liu, Shipeng Zhi, Guangzhou Li, Nan Chai, Jiaqi Huang, Yongyao Xie, Xianrong Xie, Letian Chen, Miao Gu, Yao‐Guang Liu, Qinlong Zhu   +14 more
wiley   +1 more source