Results 101 to 110 of about 230,301 (307)

A Human Immuno‐Lung Organoid Model to Study Macrophage‐Mediated Lung Cell Senescence Upon SARS‐CoV‐2 Infection

open access: yesAdvanced Science, EarlyView.
Immuno‐lung organoids are developed and used spatial transcriptomics to uncover how proinflammatory macrophages drive lung cell senescence via the THBS1–(ITGA3+ITGB1) axis in COVID‐19. To ensure broad accessibility, LungSpatialDB is created, an AI‐powered data portal, enabling intuitive exploration of spatial data and biological insights through ...
Yuling Han   +24 more
wiley   +1 more source

Characterizing Van Kampen Squares via Descent Data

open access: yes, 2012
Categories in which cocones satisfy certain exactness conditions w.r.t. pullbacks are subject to current research activities in theoretical computer science.
A. Grothendieck   +20 more
core   +2 more sources

Aberrant Mitochondrial Metabolism in Alzheimer's Disease Links Energy Stress with Ferroptosis

open access: yesAdvanced Science, EarlyView.
Alves et al. reveal how energy loss and oxidative stress, two major features of Alzheimer's disease, are connected. Mitochondria controls the flux of the antioxidant glutathione (GSH), via facilitating both its production and consumption. Energy restriction limits GSH synthesis, conferring vulnerability to cell death by ferroptosis, implicated as a ...
Francesca Alves   +17 more
wiley   +1 more source

A formal theory of conceptual modeling universals [PDF]

open access: yes, 2004
Conceptual Modeling is a discipline of great relevance to several areas in Computer Science. In a series of papers [1,2,3] we have been using the General Ontological Language (GOL) and its underlying upper level ontology, proposed in [4,5], to evaluate ...
Guizzardi, Giancarlo   +2 more
core   +3 more sources

A Wearable AI‐Driven Mask with Humidity‐Sensing Respiratory Microphone for Non‐Vocal Communication

open access: yesAdvanced Science, EarlyView.
A wearable, plug‐and‐play respiratory microphone—featuring a gold nanoparticle‐based humidity sensor—facilitates voice‐free verbal communication for patients with impaired vocal fold function. Abstract Hoarseness and dysphonia caused by vocal cord conditions or laryngeal surgeries significantly hinder communication and quality of life.
Jianfei Wang   +8 more
wiley   +1 more source

Editorial: Current thoughts on the brain-computer analogy—All metaphors are wrong, but some are useful

open access: yesFrontiers in Ecology and Evolution, 2023
Giorgio Matassi   +5 more
doaj   +1 more source

A deep learning platooning-based video information-sharing Internet of Things framework for autonomous driving systems

open access: yesInternational Journal of Distributed Sensor Networks, 2019
To enhance the safety and stability of autonomous vehicles, we present a deep learning platooning-based video information-sharing Internet of Things framework in this study.
Zishuo Zhou   +3 more
doaj   +1 more source

Idempotent Factorizations of Square-Free Integers

open access: yesInformation, 2019
We explore the class of positive integers n that admit idempotent factorizations n = p ¯ q ¯ such that λ ( n ) ∣ ( p ¯ − 1 ) ( q ¯ − 1 ) , where λ is the Carmichael lambda ...
Barry Fagin
doaj   +1 more source

Abstract State Machines 1988-1998: Commented ASM Bibliography [PDF]

open access: yes, 1998
An annotated bibliography of papers which deal with or use Abstract State Machines (ASMs), as of January 1998.Comment: Also maintained as a BibTeX file at http://www.eecs.umich.edu ...
Boerger, Egon, Huggins, James K.
core   +3 more sources

BRD4 Signaling Maintains the Differentiated State of β Cells

open access: yesAdvanced Science, EarlyView.
The comprehensive exploration revealed the critical role of BRD4 in β cells. BRD4 plays a fundamental role in maintaining β cell differentiation because both long‐term and acute BRD4 deficiency result in a reduction in insulin secretion and downregulation of differentiation markers.
Fuqiang Liu   +22 more
wiley   +1 more source

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