Results 21 to 30 of about 2,544 (181)

Von In‐Silico bis In‐Cerebro – Entwicklung des Orexinrezeptor Antagonisten „Photorexant“ zur Photomodulation In Vitro und im Gehirn der Maus

Angewandte Chemie, EarlyView.
Durch einen strukturbasierten Designansatz wurden photoschaltbare Derivate des von der FDA zugelassenen Arzneistoffes Suvorexant entwickelt, gedockt, synthetisiert und pharmakologisch an den Orexin‐1‐ und 2‐Rezeptoren (OX1R und OX2R) charakterisiert.
Marcus Angermann, Marie H. Deventer, Vicente Ledesma‐Martin, Nuno Martinho, Alix Flake, Silvia Mori, Angel Nuñez, Jaime Pignatelli, Rita C. Guedes, Christophe P. Stove, Michael Decker   +10 more
wiley   +1 more source

Impact of B and Al on the initial and residual dissolution rate of alumino-borosilicate glasses. Part I: kinetic data

npj Materials Degradation
Nuclear glasses are made of highly soluble (B) and low soluble (Si, Al) glass formers. This paper investigates the influence of these two types of elements on the initial and residual alteration rates of 6-oxide borosilicate glasses with varying B and Al
Mélanie Taron, Stéphane Gin, Jean-Marc Delaye   +2 more
doaj   +1 more source

Comparing Transcriptomic Responses to Chemicals Across Six Species Using the EcoToxChip RNASeq Database

Environmental Toxicology and Chemistry, EarlyView.
Abstract The EcoToxChip project includes RNA‐sequencing data from experiments involving model (Japanese quail, fathead minnow, African clawed frog) and ecological (double‐crested cormorant, rainbow trout, northern leopard frog) species at multiple life stages (whole embryo and adult) exposed to eight chemicals of environmental concern known to perturb ...
Krittika Mittal, Jessica Ewald, Doug Crump, Jessica Head, Markus Hecker, Natacha Hogan, Jianguo Xia, Niladri Basu   +7 more
wiley   +1 more source

A multi parameter approach for predicting initial dissolution rate of silicate glasses

npj Materials Degradation
The prediction of a glass’ initial dissolution rate (r 0 ) is crucial for various applications in industry, nuclear waste management, and healthcare. The primary limitations of existing approaches are the lack of dissolution behavior classification and ...
Faijan, Jean-Marc Delaye, Ryuki Kayano, Takahiro Ohkubo, Stéphane Gin   +4 more
doaj   +1 more source

Training of MST Educators in the context of the State of Espírito Santo

Revista Brasileira de Educação do Campo
This article is part of a doctoral research project that aims to present the trajectory of the largest social movement in Latin America, regarding the training processes of educators who work in the areas of camps and settlements of Agrarian Reform in ...
Marle Aparecida Fideles de Oliveira Vieira, Adelar João Pizetta, Valdete Côco   +2 more
doaj   +1 more source

Controlling banana bunchy top disease in Benin: Crop protection strategies with socio‐economic perspectives

PLANTS, PEOPLE, PLANET, EarlyView.
Banana and plantain are vital for food security and income in West Africa, yet banana bunchy top virus (BBTV) threatens production. This study combined remote sensing, field surveys, modelling and socio‐economic analysis to assess BBTV spread and control strategies in Benin.
Renata Retkute, Martine Zandjanakou‐Tachin, Bonaventure Aman Omondi, Ulrich Roland Agoi, Yaovi Marc Vodounou, Hermine Akofodji, Evrard Akpla, Laurence Dossou, Emiline Médénou, Alban Etchiha, Alphonse Attadéou, P. Lava Kumar, John E. Thomas, Christopher A. Gilligan   +13 more
wiley   +1 more source

Impact of B and Al on the initial and residual dissolution rate of alumino-boro-silicate glasses. Part II: gel properties

npj Materials Degradation
Physical and chemical properties of passivating alteration gels formed on alumino-boro-silicate glasses of interest for nuclear waste containment are reported.
Mélanie Taron, Stéphane Gin, Huseyin Kaya, Jean-Marc Delaye, Seong H. Kim   +4 more
doaj   +1 more source

Open letter: Brazil at a crossroads—Protecting peatlands is essential for post‐COP30 climate leadership

PLANTS, PEOPLE, PLANET, EarlyView.
This Open Letter highlights peatlands as critical yet overlooked ecosystems in Brazil's climate and biodiversity policies. By translating scientific evidence into clear, actionable priorities for policymakers, it supports more accurate climate reporting, effective mitigation strategies, and improved land‐use governance.
Suelma Ribeiro Silva, Alexandre Christofaro Silva, Uidemar Morais Barral, Carlos Moreira de Souza Jr, Renato Ramos Silva, Bruno Machado Teles Walter, Franziska Tanneberger, Geraldo Wilson Fernandes, Alexsander Araujo de Azevedo, Ana Cristina Rodrigues Lacerda, André Rodrigo Rech, Angela‐Gallego Sala, Ani Cátia Giotto, Antonio Martínez Cortizas, Barbara Pereira Christofaro Silva, Carlos Eduardo Pellegrino Cerri, Carlos Victor Mendonça Filho, Caroline Signori Müller, Cássia Beatriz Rodrigues Munhoz, Cátia Nunes da Cunha, Chesterton Ulysses Orlando Eugênio, Cristiano Christofaro Matosinhos, Danielle Piuzana Mucida, Danilo Barbuena, Diego Tassinari, Douglas Sathler dos Reis, Eneida Maria Eskinazi Sant'Anna, Esteban Terneus Jácome, Fabiane Nepomuceno Costa, Felix Beer, Guilherme Braga Ferreira, Hans Joosten, Helga Correa Wiederhecker, Ingrid Horák Terra, Jan Peters, João Bernardo de A. Bringel Jr, Kristell Hergoualc'h, Letícia Cândida Pataca, Lucia Maria Porto de Paula, Luciana de Mendonça Galvão, Maiby Glorize da Silva Bandeira, Marcelino Santos de Morais, Marcelo Brilhante de Medeiros, Matheus Kuchenbecker, Natália Rodrigues Bijos, Pablo Vidal Torrado, Patricia Roeser, Ricardo da Silva Carvalho, Rodolfo Iturraspe, Thamyres Sabrina Gonçalves, Thiago Almeida Andrade Pinto, Wilbor Poletti, Yule Roberta Ferreira Nunes   +52 more
wiley   +1 more source

Link prediction in ecological meta‐networks under extreme taxonomic bias

Methods in Ecology and Evolution, EarlyView.
Abstract Ecological networks offer powerful insights into community function but, without first characterizing these networks accurately, our ability to detect and interpret changes under environmental stress is limited. We develop an extension of the Covariate‐Informed Link Prediction (COIL) framework to reduce bias in ecological link prediction when ...
Jennifer N. Kampe, Camille M. M. DeSisto, David B. Dunson   +2 more
wiley   +1 more source

Vergleich eines 3D‐gedruckten Hautmodells mit etablierten Methoden zur Lehre der Stanzbiopsie mit Nahtversorgung

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Zusammenfassung Hintergrund Realistische Trainingsmodelle sind essenziell, um Ärztinnen und Ärzte in klinischen Prozeduren zu schulen. In dieser Studie wurde untersucht, ob ein kostengünstiges, selbst generiertes 3D‐gedrucktes Hautmodell Früchten und Schaumstoffmodellen beim Erlernen von Hautstanzen überlegen ist.
Sandra Schuh, Stefan Schiele, Anna Rubeck, Ludwig Christian Hinske, Julia Welzel, Alexander Schneller   +5 more
wiley   +1 more source