Results 61 to 70 of about 238,118 (307)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Mechanistic multilayer model for non-invasive bioimpedance of intact skin

open access: yesJournal of Electrical Bioimpedance, 2018
An approximate semi-analytical solution based on a Hankel transform of a mechanistic model for electrical impedance spectroscopy (EIS) is derived for a non-invasive axisymmetric concentric probe with m electrodes measuring the response of n layers of ...
Tsai B., Birgersson E., Birgersson U.
doaj   +1 more source

A space-time domain RBF method for 2D wave equations

open access: yesFrontiers in Physics, 2023
In the present study, we demonstrate the feasibility to reveal the numerical solution of the multi-dimensional wave equations. A simple semi-analytical meshless method was proposed to obtain the numerical solution of the wave equation with a newly ...
Fu-Zhang Wang   +4 more
doaj   +1 more source

Approximate analytic solution of heat conduction in hollow semi-spheres flying at hypersonic speed

open access: yes, 2013
Heat transfer in blunt noses of hypersonic vehicles with coolant inside can be approximately considered as heat conduction in hollow semi-sphere with aerodynamic heating on the outer boundary and enhanced cooling on the inner boundary.
姜宗林   +2 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

A numerical solution for an inverse heat conduction problem [PDF]

open access: yesIranian Journal of Numerical Analysis and Optimization, 2008
In this paper, we demonstrate the existence and uniqueness a semianalytical solution of an inverse heat conduction problem (IHCP) in the form: ut = uxx in the domain D = {(x, t)| 0 < x < 1, 0 < t T}, u(x, T) = f(x), u(0, t) = g(t), and ux(0, t) = p(t ...
Abdollah Shidfar, Ali Zakeri
doaj   +1 more source

Semi-Analytical Solution for Elastic Impact of Two Beams

open access: yesStrojarstvo : časopis za teoriju i praksu u strojarstvu, 2012
This paper presents semi-analytical solution for the problem of elastic impact of two beams. The solution is based on the finite element discretization of the structure and equation of motion solution using diagonalization method for solving a system of differential equations. This procedure avoids temporal discretization typical for numerical methods,
ČATIPOVIĆ, Ivan   +2 more
openaire   +2 more sources

Semi-analytical solution for gable roofs under uplift wind loads

open access: yes, 2021
A common type of failure observed during hurricane events is the detachment of the roofs of light-frame wood houses because of the inability of the roof-to-wall connection (RTWC) to transfer uplift wind loads acting on the roofs.
Nassef, Ashraf   +2 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Semi-analytical method for solving stresses in slope under general loading conditions

open access: yesApplied Rheology, 2023
Assessing the stress distribution within the slope in geotechnical engineering is critical. Despite the widely available numerical methods, no analytical solutions are available for determining the stress distribution within a slope under general loading
Wu Ping, Sun Xuejun, Zhu Dayong Zhu
doaj   +1 more source

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