Results 71 to 80 of about 238,118 (307)

Neumann problem on the semi-line for the Burgers equation

open access: yes, 2011
In this article, the Neumann problem on the semi-line for the Burgers equation is considered. The problem is reduced to a nonlinear integral equation in one independent variable, whose unique solution is proven to exist for small time.
Sommacal, Matteo, de Lillo, Silvana
core   +1 more source

An analytical solution for a transient temperature field during laser heating a finite slab [PDF]

open access: yes, 2016
This paper presents a general solution for the transient temperature field in a finite slab, when heated by a moving laser heat source. The analytical solution was solved by integral transform method.
彭青   +1 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Semi-analytical solutions of the Schnakenberg model of a reaction-diffusion cell with feedback

open access: yesResults in Physics, 2018
This paper considers the application of a semi-analytical method to the Schnakenberg model of a reaction-diffusion cell. The semi-analytical method is based on the Galerkin method which approximates the original governing partial differential equations ...
K.S. Al Noufaey
doaj   +1 more source

Analytical landing trajectories for embedded autonomy

open access: yes, 2010
This paper considers an optimal guidance law for the initial braking phase of a soft landing mission on a celestial body without atmosphere in which boundary conditions on height and velocity are specifed. The optimal lander attitude for the minimum fuel
Jing, W.X.   +5 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Through-thickness damage distribution in sheet bending employing the workability diagram

open access: yesВестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение
A semi-analytical solution is constructed to determine the through-thickness distribution of the average stress triaxiality parameter included in the ductile fracture criterion in sheet bending under the action of a bending moment and tensile force.
E. A. Lyamina
doaj   +1 more source

A Semi-Analytical Solution to the Schr ¨ odinger Equation with Gaussian Well

open access: yes, 2018
This paper proposes a new semi-analytical solution of the Schr¨odinger equation with Gaussian well. The approach is based on the harmonic oscillator and yields both the energy and the wave function for any specific eigenstate.
Byl, Achim
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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