Results 41 to 50 of about 350,897 (260)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

ON REGULAR SEMI-OPEN SETS AND $S^*$-CLOSED SPACES

open access: yesTamkang Journal of Mathematics, 1992
In this note, the regular semi-open sets, introduced in [2], are further investigated. Using covers consisting of such sets, a new class of topological spaces, called the $s^*$-closed spaces, is defined and studied.
Tadros, S. F., Khalaf, A. B.
openaire   +3 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Semi-Hurewicz-Type properties in ditopological texture spaces

open access: yesOpen Mathematics, 2018
In this paper we will define and discuss semi-Hurewicz type covering properties in ditopological texture spaces. We consider the behaviour of semi-Hurewicz and co-semi-Hurewicz selection properties under direlation and difunction between ditopological ...
Ullah Hafiz, Khan Moiz ud Din
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

On Micro - b ̇ - open sets and Micro - b ̇ - continuity

open access: yesTikrit Journal of Pure Science, 2020
The purpose of this research is generalize the concepts of micro  openset, so we study the relation this new concept open set micro-pre-open set, micro-semi-open set, micro  open set, and micro openset and micro open continuity and micro  irresolute ...
Taha H. Jasim, Marwah D. Sultan
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

L- pre-open and L-semi-p-open Sets

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2017
   The purpose of this paper is to study   new  types of open sets in bitopological spaces.
S. G. Gasim
doaj  

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