Results 171 to 180 of about 372,053 (263)

Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles

Advanced Science, EarlyView.
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu, Yin Dou, Chenwen Li, Yuying Mu, Huiying Ouyang, Wenhao Shen, Jianxiang Zhang   +6 more
wiley   +1 more source

Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing

Advanced Science, EarlyView.
Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu, Bayinqiaoge, Xi Lu, Xin Wang, Rongfeng Wang, Yi Li, Shi‐Yang Tang, Chengchen Zhang   +7 more
wiley   +1 more source

AI-enabled protein design facilitates future plant research and crop breeding. [PDF]

Plant Physiol
Lou Y, Wu T, Xia F, Zhao A, Wang X.
europepmc   +1 more source

A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair

Advanced Science, EarlyView.
A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao, Xinyu Wang, Zhifeng Wu, Xinya Zhang, Xiao Geng, Ti Zhang, Yue Wang, Hongwei Xia, Jun Zhang, Xianbo Qiu, Cuiru Sun, Yingjie Yu, Wenli Dai, Hua Tian, Qing Cai   +14 more
wiley   +1 more source

Evolutionary Assembly and Future Design of Gibberellin Signaling. [PDF]

Adv Sci (Weinh)
Fan W, Chen X, Li D, Gao X, Fu X.
europepmc   +1 more source

Asymmetric Electrostrain/Electrobending in Piezoelectric Ceramics: Role of Defect Dipoles or Oxygen Vacancies

Advanced Science, EarlyView.
Defect‐configurational origins of the asymmetric apparent electrostrain are revealed in different piezoelectric ceramics via atomic‐scale visualization of defect configurations. Migration of oxygen vacancies leads to the electrobending effect in N2‐sintered BaTiO3, while defect dipoles in Ba0.99TiO2.99 generate true asymmetric electrostrain without ...
Jie Wang, Geng Huangfu, Hongjie Zhang, Tiannan Yang, Zhenhua Ma, Jingsheng Chen, Yun Liu, Yiping Guo   +7 more
wiley   +1 more source

Semi-rational engineering of terminal deoxynucleotidyl transferase for high-efficiency enzymatic <i>de novo</i> DNA synthesis. [PDF]

Synth Syst Biotechnol
Zhang C, He Z, Gao Z, Meng C, Peng W, Du L, Li S.   +6 more
europepmc   +1 more source

Enhancing the thermostability of Pantoea dispersa sucrose isomerase using semi-rational design strategy

Systems Microbiology and Biomanufacturing
Huanliu Lin, Jing Wu, Sheng Chen, Kang Zhang   +3 more
openaire   +1 more source

Multifunctional TiO2‐Graphene Hybrid Interfaces for Printable High‐Energy‐Density Polymer Thin Film Capacitor

Advanced Electronic Materials, EarlyView.
ABSTRACT The rapid advancement of flexible and wearable electronics demands printable thin‐film capacitors that combine high dielectric performance with scalable fabrication. However, achieving this balance in polymer dielectrics remains challenging, as enhancements in dielectric constant typically come at the expense of increased loss and reduced ...
Yujia Fan, Yujia Li, Ruixiang Li, Shaoliang Guan, Mengyan Nie, Shahab Akhavan, Buddha Deka Boruah, Mingqing Wang   +7 more
wiley   +1 more source

From Materials to Systems: Challenges and Solutions for Fast‐Charge/Discharge Na‐Ion Batteries

Advanced Energy Materials, EarlyView.
This review systematically analyzes the key characteristics limiting the fast‐charge/discharge capability of Na‐ion batteries (SIBs) from a multi‐scale perspective encompassing electrode materials, the electrode‐electrolyte interface, and the system. Furthermore, it presents practical solution strategies for the fundamental issues arising at each scale,
Bonyoung Ku, Sangbin Park, Sunha Hwang, Sunghyun Lim, Won‐Sub Yoon, Jongsoon Kim   +5 more
wiley   +1 more source