Results 71 to 80 of about 372,053 (263)

Rigidifying Flexible Regions of a Bacterial Laccase Enables High-Temperature Aflatoxin B1 Degradation

Microorganisms
Aflatoxin B1 (AFB1) poses a serious threat to global food and feed safety. Laccase-based enzymatic degradation represents a promising green strategy for AFB1 removal; however, its industrial application is severely limited by the rapid thermal ...
Dongwei Xiong, Huiying Sun, Yuhang Sun, Peng Li, Miao Long   +4 more
doaj   +1 more source

The role of the discrete-time Kalman-Yakubovitch-Popov lemma in designing statistically optimum FIR orthonormal filter banks [PDF]

, 1998
We introduce a new approach to design FIR energy compaction filters of arbitrary order N. The optimization of such filters is important due to their close connection to the design of an M-channel orthonormal filter bank adapted to the input signal ...
Tuqan, Jamal, Vaidyanathan, P. P.
core  

Combining Subgoal Graphs with Reinforcement Learning to Build a Rational Pathfinder

, 2018
In this paper, we present a hierarchical path planning framework called SG-RL (subgoal graphs-reinforcement learning), to plan rational paths for agents maneuvering in continuous and uncertain environments.
Hu, Cong, Hu, Yue, Qin, Long, Yin, Quanjun, Zeng, Junjie   +4 more
core   +1 more source

A Physiological Microfluidic Blood–Brain‐Barrier Model for In Vitro Study of Nanoparticle Trafficking and Accumulation

Advanced Healthcare Materials, EarlyView.
A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen, Neona M. Lowe, Sophia Kellogg, Kuan‐Wei Huang, Hannah O'Toole, Elizabeth J. Hale, Venktesh S. Shirure, Bhupinder S. Shergill, Steven C. George, Randy P. Carney   +9 more
wiley   +1 more source

Enhanced l-serine synthesis in Corynebacterium glutamicum by exporter engineering and Bayesian optimization of the medium composition

Synthetic and Systems Biotechnology
l-serine is a versatile, high value-added amino acid, widely used in food, medicine and cosmetics. However, the low titer of l-serine has limited its industrial production.
Yifan Huang, Yujie Gao, Yamin Huang, Xiaogang Wang, Meijuan Xu, Guoqiang Xu, Xiaojuan Zhang, Hui Li, Jinsong Shi, Zhenghong Xu, Xiaomei Zhang   +10 more
doaj   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Effect of health belief model-based education to elder individuals on rational drug use

Medicine Science, 2020
In this study, it was aimed to determine the effects of education provided according to the health belief model on the rational use of drugs in elder individuals. Pretest-posttest single group test design was used in this semi-experimental study.
Semsinnur Gocer, Osman Gunay
doaj   +1 more source

Unveiling the Role of Curvature in Carbon for Improved Energy Release of Ammonium Perchlorate

Advanced Materials, EarlyView.
High‐curvature carbon materials identified via machine learning and simulation can enhance the heat release and combustion performance of ammonium perchlorate. ABSTRACT The catalytic role of carbon curvature in the thermal decomposition of ammonium perchlorate (AP) remains largely unexplored. To address this gap, this study employs machine learning and
Dan Liu, Keliang Song, Haorui Zhang, Zhipeng Liu, Guansong He, Junru Wang, Wenming Yang, Xu Zhao, Zhijian Yang   +8 more
wiley   +1 more source

Engineering allosteric inhibition of homoserine dehydrogenase by semi-rational saturation mutagenesis screening

Frontiers in Bioengineering and Biotechnology
Allosteric regulation by pathway products plays a vital role in amino acid metabolism. Homoserine dehydrogenase (HSD), the key enzyme for the biosynthesis of various aspartate family amino acids, is subject to feedback inhibition by l-threonine and l ...
Xinyang Liu, Xinyang Liu, Xinyang Liu, Xinyang Liu, Jiao Liu, Jiao Liu, Zhemin Liu, Zhemin Liu, Qianqian Qiao, Qianqian Qiao, Qianqian Qiao, Qianqian Qiao, Xiaomeng Ni, Xiaomeng Ni, Xiaomeng Ni, Jinxing Yang, Jinxing Yang, Guannan Sun, Guannan Sun, Fanghe Li, Fanghe Li, Wenjuan Zhou, Wenjuan Zhou, Xuan Guo, Xuan Guo, Jiuzhou Chen, Jiuzhou Chen, Shiru Jia, Shiru Jia, Yu Zheng, Yu Zheng, Ping Zheng, Ping Zheng, Ping Zheng, Jibin Sun, Jibin Sun, Jibin Sun   +36 more
doaj   +1 more source

Mechanisms for Automated Negotiation in State Oriented Domains

, 1996
This paper lays part of the groundwork for a domain theory of negotiation, that is, a way of classifying interactions so that it is clear, given a domain, which negotiation mechanisms and strategies are appropriate.
Rosenschein, J. S., Zlotkin, G.
core   +2 more sources