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Anticonvulsant semicarbazides

Journal of Medicinal Chemistry, 1968
W E, Coyne, J W, Cusic
exaly   +3 more sources

Semicarbazide Formation in Flour and Bread

Journal of Agricultural and Food Chemistry, 2008
Azodicarbonamide, an approved food additive, is commonly used as a flour additive and dough conditioner in the United States and Canada. A number of researchers have clearly established a link between the use of azodicarbonamide and semicarbazide contamination in commercial bread products.
Gregory O, Noonan   +2 more
openaire   +2 more sources

Semicarbazide in Canadian bakery products

Food Additives and Contaminants, 2006
Levels of semicarbazide were determined by liquid chromatography-tandem mass spectrometry using isotope dilution ((13)C(15)N(2)-semicarbazide) methodology, and they were measured, after hydrolysis in 0.125 M hydrochloric acid and derivatization with 2-nitrobenzaldehyde, as a sum of free and bound semicarbazide.
A, Becalski   +3 more
openaire   +2 more sources

The embryotoxic and osteolathyrogenic effects of semicarbazide

Toxicology, 1985
The osteolathyrogenic agent semicarbazide was assayed for its toxicity and teratogenicity using early embryos of the frog Xenopus laevis. The 96-h LC50 is 1504.20 mg/l while the 96-h EC50 is 76.28 mg/l. Embryo length is altered prior to the onset of other effects indicated by a reduction in stage of development.
T W, Schultz, J N, Dumont, R G, Epler
openaire   +2 more sources

Electrical, thermal and infrared studies on semicarbazide hydrochloride and semicarbazide hydrobromide

Applied Physics A Solids and Surfaces, 1992
Semicarbazide hydrochloride (SEM.HCl) was reported to be a prototype of another possible family of ferroelectrics [Appl. Phys. Lett. 20, 49 (1972)]. The present dielectric, resistivity, thermal and infrared absorption studies carried out on SEM.HCl and SEM.HBr do not confirm this suggestion.
Srinivasan, MR, Bhat, HL, Narayanan, PS
openaire   +1 more source

Potentiation of the Action of Histamine by Semicarbazide

Nature, 1951
ZELLER1 has shown that semicarbazide inhibits histaminase. We have found that this substance, added to Tyrode solution, potentiates the action of histamine on the guinea pig's ileum. The lowest concentration at which semicarbazide clearly potentiates histamine is of the order of 10−9.
J L, MONGAR, H O, SCHILD
openaire   +2 more sources

Methylated semicarbazides

Recueil des Travaux Chimiques des Pays-Bas, 1943
AbstractSemicarbazide is the common but incorrect name for carbamic acid hydrazide: magnified imageThe atom are numbered as indicated.Semicarbazide reacts readily with aldehydes and ketones, and this reaction is often used to separate those compounds from mixtures or to identify them.
openaire   +1 more source

Komplexverbindungen der Semicarbazide

Zeitschrift für anorganische und allgemeine Chemie, 1936
AbstractDie Semicarbazide bilden Komplexverbindungen, in welchen sie zwei Koordinationsstellen besetzen. Das Metall ist an das Sauerstoffatom und die Hydrazingruppe gebunden. Von Nickel wurden außer Verbindungen von den Typen [NiSem2] und [NiSem3]X3 auch rote, innerkomplexe Verbindungen erhalten, welche sich von dem Semicarbazid durch Ersatz eines ...
K. A. Jensen, E. Rancke‐Madsen
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Novel source of semicarbazide: levels of semicarbazide in cooked crayfish samples determined by LC/MS/MS

Food Additives and Contaminants, 2004
Nitrofuran antibiotics were previously used in animal healthcare but are now prohibited. Semicarbazide is a breakdown product of 5-nitrofurazone and protein-bound semicarbazide is used as a marker residue for the illegal use of 5-nitrofurazone. However, the presence of the prohibited semicarbazide has been reported in some food items of animal origin ...
L, Saari, K, Peltonen
openaire   +2 more sources

Menthone Semicarbazides and Thiosemicarbazides as Anticonvulsant Agents

Medicinal Chemistry, 2010
A series of novel (+/-) 3-menthone semi carbazides (1-7) and thiosemicarbazides synthesized using an appropriate synthetic route and characterized by thin layer chromatography and spectral analysis. The anticonvulsant activity of synthesized compounds was established after intraperitoneal administration in three seizure models in mice which include ...
Jainendra, Jain   +3 more
openaire   +2 more sources

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