Results 91 to 100 of about 458,190 (303)
Inferring transportation modes from GPS trajectories using a convolutional neural network
Identifying the distribution of users' transportation modes is an essential part of travel demand analysis and transportation planning. With the advent of ubiquitous GPS-enabled devices (e.g., a smartphone), a cost-effective approach for inferring ...
Dabiri, Sina, Heaslip, Kevin
core +1 more source
Effect of metabolic and antioxidant supplementation on sperm parameters in oligo-astheno-teratozoospermia, with and without varicocele: a double-blind placebo-controlled study [PDF]
Since sperm require high energy levels to perform their specialised function, it is vital that essential nutrients are available for spermatozoa when they develop, capacitate and acquire motility.
Agarwal, A. +8 more
core +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Utilização de extrato de própolis verde no resfriamento de sêmen equino [PDF]
Seminal cooling aims to prolong spermatic lifespan and fertilizing capacity due to reduction in energy metabolism of spermatozoa, providing enough period for transportation from the stallion to the mare.
Santos, Fernanda Carlini Cunha dos
core +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Biotecnologia reproductiva en porcí: estat actual i reptes de futur [PDF]
La biotecnologia reproductiva en porcí inclou les diverses tècniques d'anàlisi de la qualitat seminal i les tècniques de reproducció assistida. Els objectius fonamentals són garantir la seguretat biològica, permetre'n la traçabilitat i incrementar (o ...
Bonet i Marull, Sergi +12 more
core
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
El atractivo facial masculino como predictor de la calidad seminal [PDF]
Poblaciones femeninas y masculinas de España y Colombia valoraron el atractivo facial masculino en fotos de 59 individuos caucasoides. Las mujeres, identificaron como más atractivos a los hombres con mejor calidad seminal.
GUTIÉRREZ DE AGUAS, Ricardo +6 more
core
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source

