Results 41 to 50 of about 458,190 (303)

Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus, Floortje Strobbe, Annemarie A. Verrijn Stuart, Hanneke M. van Santen, Gerlof D. Valk, Sasja A. Schepers, Rachel S. van Leeuwaarde   +6 more
wiley   +1 more source

Sperm DNA integrity in leukocytospermia and its association with seminal adenosine deaminase

Journal of Human Reproductive Sciences, 2019
Background: The study aimed to examine the effect of leukocytospermia on sperm quality and the levels of seminal adenosine deaminase (ADA) enzyme in males attending an infertility clinic in a tertiary hospital and to detect the association, if any ...
Harsha Pratap, Suma Yekappa Hottigoudar, Kubera Siddappa Nichanahalli, Soundaravally Rajendran, Hanuman Srinivas Bheemanathi   +4 more
doaj   +1 more source

Editorial: Seminal Transferrin in the Seminal Quality Evaluation of Hemodialytic Patients

Endocrinology and Disorders, 2018
The Transferrin is an iron ion transport protein with a biological function that is important to avoid toxic effects due to high intra and extracellular iron ion concentrations [1]. The cellular protective function attributed to transferrin, especially to the germ and support cells (Sertoli cells), is due to its possible antioxidative function exerted ...
openaire   +1 more source

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser, Alice Bizeul, Meera Chitlur, Hugo Donato, Jelena Roganovic, Julia E. Vogt, Thomas Kühne   +6 more
wiley   +1 more source

Approximate Approximation on a Quantum Annealer

, 2020
Many problems of industrial interest are NP-complete, and quickly exhaust resources of computational devices with increasing input sizes. Quantum annealers (QA) are physical devices that aim at this class of problems by exploiting quantum mechanical ...
Feld, Sebastian, Gabor, Thomas, Linnhoff-Popien, Claudia, Mauerer, Wolfgang, Sax, Irmi, Zielinski, Sebastian   +5 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Lactotransferrin in Asian elephant (Elephas maximus) seminal plasma correlates with semen quality. [PDF]

PLoS ONE, 2013
Asian elephants (Elephas maximus) have highly variable ejaculate quality within individuals, greatly reducing the efficacy of artificial insemination and making it difficult to devise a sperm cryopreservation protocol for this endangered species. Because
Wendy K Kiso, Vimal Selvaraj, Jennifer Nagashima, Atsushi Asano, Janine L Brown, Dennis L Schmitt, John Leszyk, Alexander J Travis, Budhan S Pukazhenthi   +8 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Oxidative Stress in Seminal Plasma Negatively Influences Sperm Quality in Infertile Males

International Journal of Integrated Health Sciences, 2023
Objective: To investigate the association between malondialdehyde concentration in the seminal plasma of infertile men and sperm quality. Methods: This case-control study included 60 male participants ranging from 25-40 years old with half of them were ...
Roshan Kumar Mahat, Dhananjay Vasantrao Bhale, Vedika Rathore   +2 more
doaj   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source