Results 111 to 120 of about 231,828 (251)

A Comprehensive Microbial Gene Catalog of the Human Airway Microbiome Across Anatomical Sites and Geographic Regions

open access: yesAdvanced Science, EarlyView.
An integrated Human Airway Microbiome Gene Catalog (iHAMGC) is constructed from 12,273 metagenomic airway samples, providing a high‐resolution reference of respiratory microbial genes. The catalog enables systematic exploration of taxonomic and functional variation across airway niches and geographic regions, revealing site‐specific and region ...
Qing Zhang   +15 more
wiley   +1 more source

Environmental influences on seminal plasma: Molecular and functional insights

open access: yesThe Journal of Reproduction and Development
Seminal plasma is a pivotal regulator of reproductive success that contributes to fertility and fecundity beyond its traditionally recognized function as a vehicle for spermatozoa.
Elizabeth TORRES-ARCE   +10 more
doaj   +1 more source

Studies on the Absorption Ability of the Seminal Vesicles Part III : Influence of Sexual Hormones on the Ab s o rption Ability of the Seminal Vesicles [PDF]

open access: yes, 1957
In order to examine the relation between the sexual hormones and the absorption ability of the seminal vesicles, the influence of the former upon absorption of penicillin, streptomycin, tetracycline and chloramphenicol in the seminal vesicles were ...
木口, 充夫
core  

A Programmable Calcification Nanoplatform for Loco‐Regional Calcification‐Immune Hepatocellular Carcinoma Therapy

open access: yesAdvanced Science, EarlyView.
An in situ‐grown BP‐CaO2 nanoplatform supplies coordinated Ca2+, endogenous phosphate, and oxidative stress to convert tumor calcification from a passive endpoint into an active immune‐remodeling process. Widespread hydroxyapatite deposition is visualized by CT, while multi‐omics reveals MCOLN2 as a calcium‐responsive mediator linking biomineralization
Long Liu   +11 more
wiley   +1 more source

Regulating Droplet Dynamics via Wormlike Micelle Networks: From Splash Suppression to Precise Confined Spreading

open access: yesAdvanced Science, EarlyView.
As displayed in Graphical Abstract image.tif, a molecular‐design strategy precisely tailors high‐speed droplet dynamics through programmed surfactant co‐assembly. The structural transition into an entangled wormlike micelle network completely suppresses stochastic splashing on fibrous substrates.
Shuling Liu   +6 more
wiley   +1 more source

Studies on the Absorption Ability of the Seminal Vesicles Part I : Absorption of the Antibiotics in the Seminal Vesicles [PDF]

open access: yes, 1957
The physiological functions of the se m inal vesicles which had been generally recognized hitherto by many invnstigators were as follows : 1) Reflex to the occurrence of the sexual impulse which occurrs by filling the lumen of the seminal vesicles. 2) As
木口, 充夫
core  

A Second Pathogenic Protein, PolyGN2C‐iso2, Reveals a Dual‐Protein Pathology in Neuronal Intranuclear Inclusion Disease

open access: yesAdvanced Science, EarlyView.
This study reveals that NOTCH2NLC transcript variant 2 generates PolyGN2C‐iso2, an aggregating protein present within intranuclear inclusions of NIID patient tissues. A novel mouse model expressing PolyGN2C‐iso2 recapitulates white matter abnormalities and cognitive deficits, mechanistically linked to mitochondrial dysfunction. These findings support a
Kang Zhang   +22 more
wiley   +1 more source

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

open access: yesAdvanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong   +8 more
wiley   +1 more source

Human immunodeficiency virus infects human seminal vesicles in vitro and in vivo.

open access: yes, 2011
International audienceSemen represents the main vector of HIV dissemination worldwide, yet the origin of HIV in semen remains unclear. Viral populations distinct from those found in blood have been observed in semen, indicating local viral replication ...
Dejucq-Rainsford, Nathalie   +11 more
core   +1 more source

Trafficking Deficiency of TMEM175 Variants in Parkinson's Disease Pathogenesis and the Prospects of Precision Medicine

open access: yesAdvanced Science, EarlyView.
This study identifies that the PD‐associated TMEM175‐L156P variant disrupts lysosomal ion channel trafficking by causing aberrant endoplasmic reticulum retention. A “chaperone–agonist” bifunctional small molecule restores TMEM175‐L156P lysosomal localization and channel function, thereby alleviating PD‐relevant cellular phenotypes and highlighting a ...
Ting Luo   +17 more
wiley   +1 more source

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