Effects of α-Linolenic Acid on Seminiferous Tubule Morphology and UCHL1-Positive Cells in Cultured Testicular Tissue Fragments from a 3-Month-Old Hu Ram: A Pilot Study [PDF]
Animalsα-linolenic acid (ALA) has been reported to benefit testicular function. However, dietary ALA is extensively metabolized in the rumen, whereas isolated cell models do not retain seminiferous tubule structure or interactions among testicular cells.
Rongyu Yao +3 more
doaj +2 more sources
Deep-learning-based automated prediction of mouse seminiferous tubule stage by using bright-field microscopy [PDF]
Scientific ReportsInfertility is a global issue, and approximately 50% of cases are due to male factors, with defective spermatogenesis being the main one. For studies of spermatogenesis, evaluating the seminiferous tubule stage is essential.
Yuta Tokuoka +5 more
doaj +2 more sources
Kaliandra honey improves testosterone levels, diameter and epithelial thickness of seminiferous tubule of white rat (Rattus norvegicus) due to malnutrition through stimulation of HSP70 [PDF]
Open Veterinary Journal, 2021 Background: Malnutrition can cause an increase in oxidative stress as it triggers the expression of Heat Shock Protein70 (HSP70), a chaperon molecule that is needed to repair damaged cells within optimal levels.
Nefranindy Rahma +5 more
doaj +2 more sources
Chitosan and Chitosan Oligosaccharide Enhance Cryopreservation of Rabbit Testicular Tissue [PDF]
BiologyTesticular tissue cryopreservation is a key strategy for preserving fertility in adult males, yet optimal cryoprotective protocols have yet to be established.
Yinlin Yao +7 more
doaj +2 more sources
Cryopreservation of human spermatozoa by freezing testicular seminiferous tubule with novel cryopiece [PDF]
Andrologia, 2022 Beihong Zheng, Feng Lin
exaly +2 more sources
Histological Findings in Testes of Baboons (Papio spp.) and Dwarf Bucks (Capra hircus) Subject to Repeated Immunisation Against GnRH. [PDF]
Vet Med SciLong‐term repeated immunisation against GnRH resulted in the absence of active spermatogenesis and may lead to irreversible infertility in dwarf bucks and baboons. Histological examination revealed a marked reduction of the seminiferous tubular lumen, complete depletion of germ cells, germ cell vacuolization and tubular hyalinization.
Ferrín T +8 more
europepmc +2 more sources
Effects of a standardized 40% ellagic acid pomegranate (Punica granatum L.) extract on seminiferous tubule histopathology, diameter, and epithelium thickness in albino Wistar rats after heat exposure [PDF]
Veterinary World, 2019 Background and Aim: It has long been known that the spermatogenic tissue is very sensitive to temperatures higher than its physiologic temperature and causing cessation of activity and resulting in sterility.
Budi Utomo +3 more
doaj +2 more sources
Humanin ameliorates diabetes-induced testicular damage in a streptozotocin-induced mouse model. [PDF]
Exp PhysiolAbstract Diabetes mellitus is a major metabolic disorder closely associated with oxidative stress and male reproductive dysfunction. Humanin, a mitochondria‐derived peptide, has been reported to exert cytoprotective, anti‐apoptotic and antioxidant effects in various disease models; however, its role in diabetes‐induced testicular damage remains unclear.
Hekim MG, Kaya Tektemur N, Ozcan M.
europepmc +2 more sources
Context-dependent effects of whole-body vibration on reproductive function and penile tissue integrity in sedentary male rats. [PDF]
Exp PhysiolAbstract Sedentary behaviour is increasingly recognized as a risk factor for systemic disorders; however, its effects on male reproductive health and penile tissue integrity remain insufficiently understood. Furthermore, the therapeutic role of whole‐body vibration (WBV) has not been investigated. This study evaluated the effects of sedentary behaviour
Ayva M +8 more
europepmc +2 more sources
Three-dimensional morphological analysis of spermatogenesis in aged mouse testes
Scientific Reports, 2021 Spermatogenesis, which is a continuous process from undifferentiated spermatogonia to spermatozoa in the seminiferous tubules, declines with age. To investigate changes in spermatogenesis with aging, we reconstructed the seminiferous tubules of 12 mice ...
Taito Nakano +11 more
doaj +1 more source