Results 161 to 170 of about 2,734 (196)

Toxic effects of Senecio brasiliensis on rat phagocytes

Toxicology Letters, 2010
s / Toxicology Letters 196S (2010) S37–S351 S199 P205-022 Allergen-stimulated expression of interleukin (IL)-17 isoforms in mice I. Kimber, M. Hayes, R. Dearman University of Manchester, United Kingdom The development of immune and allergic responses is orchestrated by T helper (Th) subsets that are characterized by selective cytokine secretion ...
F. Elias, I. Hueza, A. Latorre, S. Gorniak   +3 more
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Quantification of pyrrolizidine alkaloids in Senecio brasiliensis, beehive pollen, and honey by LC-MS/MS

Journal of Environmental Science and Health, Part B, 2021
This article presents the determination of eight pyrrolizidine alkaloids (PAs) by LC-MS/MS in honeys, pollen, and Senecio brasiliensis (Asteraceae) samples, all from Santa Catarina state, Brazil. In addition, the Box-Behnken design was used to perform an optimized sample preparation on pollens and S. brasiliensis parts.
Andressa Camargo Valese, Heitor Daguer, Carmen Maria Oliveira Muller, Luciano Molognoni, Cynthia Fernandes Pinto da Luz, Daniel de Barcellos Falkenberg, Luciano Valdemiro Gonzaga, Patricia Brugnerotto, Silvana Lima Gorniak, Fabiano Barreto, Roseane Fett, Ana Carolina Oliveira Costa   +11 more
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New records of pyrrolizidine alkaloid-feeding insects. Hemiptera and Coleoptera on Senecio brasiliensis

Biochemical Systematics and Ecology, 2000
New records are reported for a Hemipteran (Largus rufipennis) and a Coleopteran (Chauliognathus fallax) feeding on Senecio brasiliensis (Asteraceae) and sequestering pyrrolizidine alkaloids (PAs). Both insects are warningly colored and rejected by predators.
, Klitzke, , Trigo
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Induction of micronuclei by alkaloids extracted from Senecio brasiliensis and stored for 23 years

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2002
In the present study, we report the results of an investigation on pyrrolizidine alkaloids extracted from Senecio brasiliensis (Sprengel) Less., which were stored for more than 23 years under variable conditions of temperature and humidity and exposed to light.
R, Santos-Mello, L I, Deimlimg, C M, Lauer Júnior, A, Almeida   +3 more
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Recombinagenic activity of integerrimine, a pyrrolizidine alkaloid fromSenecio brasiliensis, in somatic cells ofDrosophila melanogaster

Environmental and Molecular Mutagenesis, 1997
Integerrimine (ITR), a pyrrolizidine alkaloid from Senecio brasiliensis, was tested for genotoxicity using the wing somatic mutation and recombination test (SMART) in Drosophila melanogaster. The compound was administered by chronic feeding (48 hours) of 3-day-old larvae.
V R, Campesato, U, Graf, M L, Reguly, H H, de Andrade   +3 more
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Modulatory effect of Senecio brasiliensis (Spreng) Less. in a murine model of inflammation induced by carrageenan into the pleural cavity

Journal of Ethnopharmacology, 2015
Senecio brasiliensis (Spreng) Less (S. brasiliensis), known as "Flor-das-almas", "Margaridinha" or "Maria mole", is used in folk medicine as an anti-inflammatory and to treat gastric ulcers and stomach pain. While the Senecio genus has been widely studied for its pharmacological activities to support its use in traditional medicine, few studies focus ...
Renata Rodrigues, de Souza, Lizandra Czermainski, Bretanha, Eduardo Monguilhott, Dalmarco, Moacir Geraldo, Pizzolatti, Tânia Silvia, Fröde   +4 more
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Modulation of gastrin and epidermal growth factor by pyrrolizidine alkaloids obtained fromSenecio brasiliensisin acute and chronic induced gastric ulcers

Canadian Journal of Physiology and Pharmacology, 2004
We investigated the antiulcerogenic activity of pyrrolizidine alkaloids (PAs) integerrimine, retrorsine, senecionine, usaramine and seneciplhylline, an alkaloidal extract obtained from Senecio brasiliensis. The PA extract demonstrated significantly activity in both, acute and chronic gastric ulcers on rats. The effects of PA extract were dose dependent.
Walber, Toma, José Roberto, Trigo, Ana Cláudia, Bensuaski de Paula, Alba Regina, Monteiro Souza Brito   +3 more
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Prenatal exposure to integerrimine N‐oxide enriched butanolic residue from Senecio brasiliensis affects behavior and striatal neurotransmitter levels of rats in adulthood

International Journal of Developmental Neuroscience, 2015
AbstractPyrrolizidine alkaloids (PAs) are toxins that are exclusively biosynthesized by plants and are commonly present in foods and herbs. PAs are usually associated with poisoning events in livestock and human beings. The aim of the present study was to evaluate the behavioral and neurochemical effects of prenatal exposure to PA integerrimine N‐oxide
Thaísa M, Sandini, Mariana S B, Udo, Thiago M, Reis-Silva, Daniel, Sanches, Maria Martha, Bernardi, Jorge Camilo, Flório, Helenice de S, Spinosa   +6 more
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Supercritical CO2 extraction of compounds from different aerial parts of Senecio brasiliensis: Mathematical modeling and effects of parameters on extract quality

The Journal of Supercritical Fluids, 2019
Abstract Senecio brasiliensis aerial parts extracts were obtained using supercritical carbon dioxide (SC-CO2) extraction. The objective was to evaluate the effects of temperature and pressure on the yield, extraction kinetics, and chemical composition. The extractions with SC-CO2 were performed at 15, 20 and 25 MPa, and 40, 50 and 60 °C.
Tássia C. Confortin, Izelmar Todero, Nicholas I. Canabarro, Luciana Luft, Gustavo A. Ugalde, José Roberto C. Neto, Marcio A. Mazutti, Giovani L. Zabot, Marcus V. Tres   +8 more
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Pyrrolizidine Alkaloids from Senecio brasiliensis Populations

Journal of Natural Products, 1987
G. Schmeda Hirschmann, E. A. Ferro, L. Franco, L. Recalde, C. Theoduloz   +4 more
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