Results 111 to 120 of about 32,696 (317)

Assessment of Peripheral Blood Mononuclear Cells Senescence and Endothelial Dysfunction among Adults with High Cardiovascular Risk. [PDF]

Arq Bras Cardiol, 2021
Raj V, Charles S, Goenka L, Ramamoorthy T, C M, C E, Mala K, Kumarasamy S, George M.   +8 more
europepmc   +1 more source

Herborização de orgãos vegetais em condições refrigeradas. [PDF]

, 2013
bitstream/item/30308/1/boletim-39 ...
CASTRO, L. A. S. de, CASTRO, R. C. de, COUTO, M. E. O.   +2 more
core   +1 more source

Papel homeostático e inflamatorio de neutrófilos senescentes [PDF]

, 2017
Los neutrófilos son los leucocitos más abundantes en la circulación humana y representan la primera barrera de defensa contra microorganismos patógenos. Su número en circulación muestra un comportamiento temporalmente oscilatorio, con una periodicidad circadiana.
openaire   +1 more source

The SASP factor IL‐6 sustains cell‐autonomous senescent cells via a cGAS‐STING‐NFκB intracrine senescent noncanonical pathway

Aging Cell
Senescent cells produce a Senescence‐Associated Secretory Phenotype (SASP) that involves factors with diverse and sometimes contradictory activities. One key SASP factor, interleukin‐6 (IL‐6), has the potential to amplify cellular senescence in the SASP ...
Florencia Herbstein, Melanie Sapochnik, Alejandra Attorresi, C. Pollak, Sergio Senin, David Gonilski-Pacin, Nicolas Ciancio del Giudice, M. Fiz, Belén Elguero, Mariana Fuertes, Lara Müller, M. Theodoropoulou, Lucas B. Pontel, Eduardo Arzt   +13 more
semanticscholar   +1 more source

Cellular Senescence: Aging, Cancer, and Injury.

Physiological Reviews, 2019
Cellular senescence is a permanent state of cell cycle arrest that occurs in proliferating cells subjected to different stresses. Senescence is, therefore, a cellular defense mechanism that prevents the cells to acquire an unnecessary damage.
A. Calcinotto, J. Kohli, E. Zagato, L. Pellegrini, M. Demaria, A. Alimonti   +5 more
semanticscholar   +1 more source

A Human Kidney Tubuloid Model of Repeated Cisplatin‐Induced Cellular Senescence and Fibrosis for Drug Screening

Advanced Healthcare Materials, EarlyView.
Replicating aging and senescence‐related pathophysiological responses in kidney organoids remains a significant challenge. Human adult renal tubular organoid, tubuloids, are successfully developed recapitulating cellular senescence that is the central pathophysiological mechanism of chronic kidney disease (CKD).
Yuki Nakao, Makiko Mori, Yuta Sekiguchi, Iori Morita, Ryota Shindoh, Shintaro Mandai, Tamami Fujiki, Hiroaki Kikuchi, Fumiaki Ando, Koichiro Susa, Takayasu Mori, Ayumi Suzuki, Yuji Nashimoto, Hirokazu Kaji, Yuma Waseda, Soichiro Yoshida, Yasuhisa Fujii, Eisei Sohara, Shinichi Uchida, Kensuke Miyake, Yutaro Mori   +20 more
wiley   +1 more source

[Geroscience in times of global pandemic by COVID-19]. [PDF]

Rev Esp Geriatr Gerontol, 2021
Castro-Fuentes R, Castro-Hernández J, Socas-Pérez R.   +2 more
europepmc   +1 more source

Liberación de sustancias en células senescentes

, 2012
Peer ...
Martínez Máñez, Ramón, Murguía, José Ramón, Perona Abellón, Rosario, Agostini, Alessandro, Mondragón Martínez, Laura, Moreno Torres, Marta, Manguan-García, Cristina, Marcos, M. Dolores, Soto, Joan, Sancenón, Félix   +9 more
openaire   +2 more sources

Ultrasound‐Triggered Gelation for Restoring Biomechanical Properties of Degenerated Functional Spinal Units

Advanced Healthcare Materials, EarlyView.
This study introduces an innovative approach to treating intervertebral disc degeneration using ultrasound‐triggered in situ hydrogel formation. Proof‐of‐concept experiments using optimized biomaterial and ultrasound parameters demonstrate partial restoration of biomechanical function and successful integration into degenerated disc tissue, offering a ...
Veerle A. Brans, Anna P. Constantinou, Matthew J. Kibble, Valeria Nele, Daniel Reumann, Luca Bau, Sebastien J. P. Callens, James P. K. Armstrong, Nicolas Newell, Constantin C. Coussios, Molly M. Stevens, Michael D. Gray   +11 more
wiley   +1 more source

Evolution and structure of Artikutza, an 80-year-old beech forest in navarra (northern Spain) [PDF]

Munibe Ciencias Naturales, 2009
Se ha estudiado la estructura forestal y la historia del hayedo de Artikutza. El objetivo ha sido analizar la evolución natural y recuperación del bosque tras 80 años sin intervenciones significativas.
Castro Gil, A.
doaj