Results 141 to 150 of about 1,180 (262)

Inhibición de la secreción de citocinas proinflamatorias del SASP de astrocitos de rata Wistar inducidos a senescencia prematura

open access: yes, 2019
El envejecimiento es un proceso natural en la vida de los organismos en el que disminuyen de manera gradual, sus capacidades físicas y mentales, aumentando el riesgo de padecer enfermedades crónicas y crónico-degenerativas.
LUIS ANGEL MACIEL BARON
core   +2 more sources

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

open access: yesAdvanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao   +25 more
wiley   +1 more source

Factores locales y su relación con lesiones bucales en ancianos portadores de prótesis totales

open access: yesMedisan
Se realizó un estudio descriptivo y transversal de 96 senescentes portadores de prótesis totales, atendidos en la Clínica Estomatológica "Lidia Doce Sánchez" de Guantánamo, desde enero de 2014 hasta abril de 2015, con vistas a determinar la relación ...
Marcia Hortensia Corona Carpio   +4 more
doaj  

ESTUDIO DE LAS COMUNIDADES FUNGICAS DE LA FILOSFERA DE PINUS TAEDA L. (PINACEAE) I: VARIACION ESTACIONAL STUDIES OF THE FUNGAL COMMUNITIES OF THE PHYLLOSPHERE OF PINUS TAEDA L. (PINACEAE) I

open access: yesGayana: Botanica, 2001
Estudio de las comunidades fúngicas de la filósfera de Pinus taeda L. (Pinaceae) I. Variación Estacional. Las comunidades fúngicas de las hojas son dinámicas en el tiempo y el espacio.
N. Venedikian   +2 more
doaj  

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

open access: yesAdvanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu   +7 more
wiley   +1 more source

EQUILÍBRIO ESTÁTICO E DINÂMICO EM INDIVÍDUOS SENESCENTES E O ÍNDICE DE MASSA CORPORAL

open access: yes, 2008
O estudo objetivou analisar o equilíbrio estático e o dinâmico em indivíduos senescentes e verificar sua associação com a idade e com o Índice de Massa Corporal (IMC).
José Rubens Rebelatto   +3 more
core  

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

open access: yesAdvanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma   +12 more
wiley   +1 more source

A Skull Bone Marrow‐to‐Brain Axis Links Osteoblastic Activity to Myeloid Cell Trafficking, Cerebral Blood Flow, and Cognition in Alzheimer's Progression

open access: yesAdvanced Science, EarlyView.
This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong   +6 more
wiley   +1 more source

O papel das galhas senescentes sobre a estrutura de comunidades de formigas arbóreas em Eremanthus erythropappus (DC.) MacLeish (Asteraceae).

open access: yes, 2015
Programa de Pós-Graduação em Ecologia de Biomas Tropicais. Departamento de Biodiversidade, Evolução e Meio Ambiente, Instituto de Ciências Exatas e Biológicas, Universidade Federal de Ouro Preto.A grande ocorrência de formigas na copa das árvores pode ...
Santos, Leonardo Rodrigues dos
core  

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