Results 21 to 30 of about 294 (222)

Mise en évidence d'anthocyanes dans les feuilles vertes de Cabernet Sauvignon

OENO One, 1986
Chez la Vigne, les feuilles des parties médiane et apicale des rameaux principaux jouent un rôle important dans l'apparition de la coloration anthocyanique des pellicules des raisins rouges (DARNÉ et GlORIES, 1986).
Gérard Darné
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Quality of life among elderly participants in social centers: an integrative review / Qualidade de vida em idosos participantes de centros de convivência: uma revisão integrativa

Revista de Pesquisa Cuidado é Fundamental Online, 2021
Objetivo: analisar as produções científicas acerca da participação dos idosos integrantes de Centros de Convivência para Idosos e a influência destes na qualidade de vida dos participantes.
Anne Carolinne Marie dos Santos Gomes, Kaline De Araújo Medeiros, Ana Karla Maciel Soares, Rossana de Rocci Alves Barbosa Costa, Kay Francis Leal Vieira, Adriana Lira Rufino de Lucena   +5 more
doaj   +4 more sources

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Decomposição e liberação de nitrogênio, fósforo e potássio de resíduos da cultura do feijoeiro Decomposition and release of nitrogen, phosphorus and potassium from residues of common bean crop

Revista Brasileira de Ciência do Solo, 2007
Este trabalho teve como objetivo mensurar a velocidade de decomposição e de liberação de nutrientes in situ de resíduos da cultura do feijoeiro (Phaseolus vulgaris L.).
Eduardo Chagas, Adelson Paulo Araújo, Marcelo Grandi Teixeira, José Guilherme Marinho Guerra   +3 more
doaj   +1 more source

Quality of life among elderly participants in social centers: an integrative review / Qualidade de vida em idosos participantes de centros de convivência: uma revisão integrativa

Revista de Pesquisa Cuidado é Fundamental Online, 2020
Objetivo: analisar as produções científicas acerca da participação dos idosos integrantes de Centros de Convivência para Idosos e a influência destes na qualidade de vida dos participantes.
Anne Carolinne Marie dos Santos Gomes, Kaline De Araújo Medeiros, Ana Karla Maciel Soares, Rossana de Rocci Alves Barbosa Costa, Kay Francis Leal Vieira, Adriana Lira Rufino de Lucena   +5 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source