Results 121 to 130 of about 1,180 (262)

Iron Deficiency in Heart Failure with Reduced Ejection Fraction: Pathophysiology, Diagnosis and Treatment. [PDF]

Arq Bras Cardiol, 2022
Pereira GAR, Beck-da-Silva L.
europepmc   +1 more source

Dual Cytoplasmic and Chloroplastic Mechanisms Fine‐Tune Chloroplast Division through ARC3 Protein Stability

Advanced Science, EarlyView.
ARC3 levels are controlled by cytosolic and chloroplast proteolytic systems. PUB52 mediates ARC3 precursor ubiquitination and degradation in the cytosol, while CLPC1 promotes ARC3 degradation in chloroplasts, where ARC2 protects ARC3 from excessive breakdown. Disrupting these components causes chloroplast division defects, placing them upstream of ARC3.
Yang Yuan, Denghao Xiang, Ruiying Li, Zhichuang Yue, Zhipeng Wang, Honghong Hu   +5 more
wiley   +1 more source

Estudio observacional, descriptivo, en el que se evalúa la relación de las células senescentes y otros marcadores tisulares en la fractura osteoporótica de cadera

, 2023
La osteoporosis es una enfermedad generalizada del esqueleto que se caracteriza por una disminución de la resistencia ósea que predispone a un alto riesgo de fractura. La senescencia celular es el proceso inducido por varios tipos de estrés que causan
Pena Larrea, Lorena
core  

Diabetes en el senescente: resumen

Medwave, 2001
Manuel García De los Ríos, Pilar Durruty   +1 more
openaire   +1 more source

FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3‐Mediated ErbB3 Fucosylation in Lung Adenocarcinoma

Advanced Science, EarlyView.
ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen, Jintao Guo, Fei Li, Mingjie Gao, Runyang Li, Zhaozhang Huang, Yaolin Zheng, Chunyi Gao, Jihuan Hou, Qiang Yu, Bowen Zheng, Xuemei Chen, Wenqing Zhang, Xiaoting Hong, Yali Zheng, Daxuan Wang, Qiyuan Li, Tianhui Hu, Yan‐yan Zhan   +18 more
wiley   +1 more source

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

Advanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan, Runze Yang, Ting Zhou, Tianhao Xu, Yongqi Li, Yuelin Hu, Minghao Ge, Lei Zhang, Xiong Lu, Chaoming Xie, Weili Fu   +10 more
wiley   +1 more source

Reabsorção de nutrientes por espécies arbóreas acumuladoras de fósforo na Amazônia: influência na qualidade da serrapilheira.

Revista Brasileira de Agroecologia, 2009
A importância de se conhecer as concentrações e os estoques de nutrientes como o fósforo (P) e o nitrogênio (N) na serrapilheira (liteira) produzida por espécies potencialmente acumuladoras de fósforo em florestas secundárias cujos solos são deficientes
Patricia Chaves de Oliveira, Claudio José Reis de Carvalho   +1 more
doaj  

Diabetes en el senescente: tratamiento

Medwave, 2001
Manuel García De los Ríos, Pilar Durruty   +1 more
openaire   +1 more source

Achieving High‐Density and Stress‐Resilient Maize Breeding Via Germplasm Innovation

Advanced Science, EarlyView.
Global population growth and climate change have exacerbated the global food crisis. This perspective presents a conceptual framework focusing on enhancing population advantages. Several novel breeding objectives are proposed to improve density tolerance and stress resistance for yield improvement.
Xinlong Li, Yongqiang Chen, Dong Ding, Xuehai Zhang, Xuxiang Jia, Zhanhui Zhang, Yafei Wang, Weihua Li, Hui Zhang, Jihua Tang   +9 more
wiley   +1 more source

Factores determinantes de un aumento de afinidad al oxígeno aparente en los eritrocitos humanos senescentes

, 2004
En el presente trabajo se ha re-investigado la vieja interrogante de una posible deficiencia en la liberación de oxígeno por los eritrocitos humanos senescentes, estudiando algunos factores que afectan la afinidad hemoglobina-oxígeno en células ...
Romero, Eneida A., Romero, Pedro J.
core