Results 71 to 80 of about 1,556 (255)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Senólisis en el corazón senescente: Una revisión de la literatura actual

Revista Científica CMDLT
La senescencia celular se ha consolidado como un mecanismo biológico fundamental en la patogénesis de las enfermedades cardiovasculares (ECV) asociadas al envejecimiento.
Luis Armando Tirado Fontaines, Daniel Ernesto Foldats   +1 more
doaj   +2 more sources

Decomposição in situ de folhas senescentes de pereira (Pyrus communis L. cv. Rocha) In situ decomposition of pear (Pyrus communis L. cv. Rocha) senescent leaves

Revista de Ciências Agrárias, 2007
Estudou-se a variação da perda de peso e a contribuição das folhas senescentes de pereira (cv. Rocha) para a restituição de azoto (N) ao solo através da técnica dos sacos de decomposição in situ, colocados em Outubro de 2003 à superfície do solo dum ...
C. Neto, C. Carranca, A. de Varennes, J. Clemente, J. Sobreiro   +4 more
doaj  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

[Cell senescence, a new target for respiratory viral infections: From influenza virus to SARS-CoV-2]. [PDF]

Bull Acad Natl Med, 2023
Adnot S, Bernard D, Lipskaia L, Trottein F.   +3 more
europepmc   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

[Discussion about the presentation: "Cell senescence, a new target for respiratory viral infections: from influenza virus to SARS-CoV-2"]. [PDF]

Bull Acad Natl Med, 2023
Adnot S.
europepmc   +1 more source

A desprezível correlação entre cargas internas e externas em mulheres senescentes.

REVISA
Objetivo: Pesquisas sugerem relação entre eletroestimulação e treinamento de força para otimizar a função neuromuscular, mas os efeitos das diferentes configurações geram incertezas sobre variáveis manipuláveis, incluindo cargas internas e externas.
Isabelle Cardoso da Silva, Rhamille Lima Silva, Dhianey de Almeida Neves, Noriberto Barbosa da Silva, Margo Gomes de Oliveira Karnikowski, Leonardo Costa Pereira   +5 more
openaire   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source