Results 41 to 50 of about 1,180 (262)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Avaliação in vitro da transição epitélio-mesênquima do carcinoma epidermoide de boca influenciado por fibroblastos orais senescentes

open access: yes, 2023
Seminário de Iniciação Científica e Tecnológica. Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Departamento de Ciências Morfológicas.Sabe-se que a carcinogênese oral não é dependente exclusivamente de mutações genéticas nas ...
Thiesen, Letícia
core  

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Remoción mecánica del material senescente para la recuperación de pasturas

open access: yesAgronomía Mesoamericana, 2019
Introducción. La acumulación de material senescente en pasturas tropicales es resultado de la alta producción de biomasa y bajo nivel de aprovechamiento en pastoreo. La remoción de senescencia en pasturas permite que el ganado acceda a estratos bajos durante el pastoreo, lo que genera un rebrote con mayor concentración de nutrientes. Objetivo.
Rodolfo WingChing-Jones   +1 more
openaire   +6 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Maltrato en el paciente geriátrico hospitalizado. Hospital Provincial General "Camilo Cienfuegos". Sancti Spíritus. 2008-2009.

open access: yesGaceta Médica Espirituana, 2017
Introducción: El abuso hacia los adultos mayores es un problema social y sanitario en aumento debido al incremento de: la expectativa de vida, los avances terapéuticos que prolongan la supervivencia y la pérdida de valores familiares tradicionales ...
Tamara Álvarez Gómez
doaj  

Leaf senescence of common bean plants as affected by soil phosphorus supply Senescência foliar do feijoeiro afetada pelo suprimento de fósforo no solo

open access: yesRevista Brasileira de Ciência do Solo, 2007
Responses of leaf senescence to P supply could constitute adaptive mechanisms for plant growth under P-limiting conditions. The aim of this study was to evaluate the effects of soil P supply on leaf senescence of common bean (Phaseolus vulgaris L ...
Adelson Paulo Araújo   +2 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Cellular senescence in skeletal muscle regeneration, ageing and disease [PDF]

open access: yes, 2022
Este proyecto se centra en el papel de las células senescentes durante la regeneración muscular desde varios ángulos. Para llevarlo a cabo, hemos desarrollado una técnica novedosa para poder aislar células senescentes generadas in vivo a partir de tejido
Moiseeva, Victoria
core   +1 more source

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