Results 71 to 80 of about 293 (222)

Mesenchymal Stromal Cell‐Mediated Intercellular Communication: Mapping the Interactome for Skeletal Muscle Homeostasis and Regeneration

open access: yesAdvanced Science, EarlyView.
Liu et al. define a systems‐level interactome of fibroadipogenic progenitor (FAP)‐mediated signaling in skeletal muscle by integrating single‐cell transcriptomics with FAP depletion‐based perturbation analysis. Functional interrogation using a conditioned media bioassay links predicted signaling to multicellular outcomes, establishing a framework to ...
Xingyu Liu   +13 more
wiley   +1 more source

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

open access: yesAdvanced Science, EarlyView.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia   +17 more
wiley   +1 more source

Impacto da aplicação de efluente maturado de fecularia de mandioca em solo e na cultura do sorgo - DOI: 10.4025/actasciagron.v26i4.1801

open access: yesActa Scientiarum. Agronomy, 2008
O presente trabalho teve como objetivo avaliar o comportamento da cultura do sorgo submetida a doses de efluente maturado de fecularia de mandioca. Realizou-se o presente trabalho no Centro Técnico de Irrigação da Universidade Estadual de Maringá, Estado
Frederico Fonseca da Silva   +4 more
doaj   +1 more source

m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis

open access: yesAdvanced Science, EarlyView.
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang   +26 more
wiley   +1 more source

Unveiling Lactylation: A Novel Frontier in Cancer Stemness and Therapy

open access: yesAdvanced Science, EarlyView.
Tumor metabolism and epigenetic regulation are intrinsically linked. This review highlights lactylation as a pivotal bridge connecting these processes, acting as an active epigenetic effector in cancer stemness. We delineate how lactylation orchestrates the cancer stem cell landscape and evaluate its regulatory networks.
Ting Li   +9 more
wiley   +1 more source

Actividad antialimentaria e insecticida de un extracto de hojas senescentes de Melia azedarach (Meliaceae) Antifeedant and insecticide activity of an extract from senescent leaves of Melia azedarach (Meliaceae)

open access: yesRevista de la Sociedad Entomológica Argentina, 2003
Continuando con la búsqueda de nuevos insecticidas naturales obtenidos de plantas, se estudió la actividad de un extracto de hojas senescentes (amarillas) de Melia azedarach L. (Meliaceae).
Graciela Valladares   +4 more
doaj  

Decomposição in situ de folhas senescentes de pereira (Pyrus communis L. cv. Rocha)

open access: yes, 2007
Revista de Ciências Agrárias, vol. 30 n.º 2 (2007)
Neto,C.   +4 more
openaire   +2 more sources

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Factores locales y su relación con lesiones bucales en ancianos portadores de prótesis totales

open access: yesMedisan, 2017
Se realizó un estudio descriptivo y transversal de 96 senescentes portadores de prótesis totales, atendidos enla ClínicaEstomatológica“Lidia Doce Sánchez” de Guantánamo,  desde enero de 2014 hasta abril de 2015, con vistas a determinar la relación entre ...
Marcia Hortensia Corona Carpio   +4 more
doaj  

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