Results 171 to 180 of about 1,556 (255)
Influência do diabetes mellitus no coração de ratos senescentes espontaneamente hipertensos
, 2014 As doenças cardiovasculares (DCV) são responsáveis por alta taxa de morbidade e mortalidade, tanto em países desenvolvidos como em desenvolvimento e, com o envelhecimento da população, a prevalência de seus fatores de risco está aumentando em ritmo alarmante.
openaire +1 more source
Advanced Science, EarlyView.The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang +12 more
wiley +1 more source
[The role of immunosenescence and inflammaging in aging-associated diseases]. [PDF]
Rev Med Inst Mex Seguro SocGarcía-de la Rosa MT +2 more
europepmc +1 more source
Diabetes en el senescente: definiciones, patogénesis, clínica y control
Medwave, 2001 Manuel García De los Ríos +1 more
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Advanced Science, EarlyView.Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon +6 more
wiley +1 more source
Perspectivas de uso de células-tronco em cirurgia vascular. [PDF]
J Vasc Bras, 2016 Bertanha M.
europepmc +1 more source
Advanced Science, EarlyView.Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie +12 more
wiley +1 more source
Advanced Science, EarlyView.Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa +11 more
wiley +1 more source
Influencia del ejercicio físico desde los Círculos de Abuelos en senescentes diabéticos
, 2012 Fundamento: La inactividad y las alteraciones de la movilidad resultan problemas comunes en la población adulta mayor. Objetivo: determinar la influencia del ejercicio físico en pacientes diabéticos mediante la participación en los círculos de abuelos ...
Santana Rivero, Leidy María +4 more
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