Results 181 to 190 of about 1,180 (262)

[Age-dependent oxidative stress: toward an irreversible failure in endothelial maintenance]. [PDF]

Med Sci (Paris), 2010
Thorin-Trescases N, Voghel G, Farhat N, Drouin A, Gendron MÈ, Thorin E.   +5 more
europepmc   +1 more source

LXII Congreso Nacional de la SEHH, XXXVI Congreso Nacional de la SETH Virtual, 26-30 de octubre, 2020. [PDF]

Haematologica, 2020
The Authors.
europepmc   +1 more source

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

Advanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu, Zhihao Zhan, Xiaoxiang Pan, Xinyue Zhang, Penggang Liu, Jing Sun, Xiulong Xu   +6 more
wiley   +1 more source

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

SPADE: A Deep Learning Framework for Spatial Mapping and Quantitative Cell–Cell Interaction Inference

Advanced Science, EarlyView.
SPADE integrates spatial transcriptomics with single‐cell RNA sequencing by using cell–cell communications (CCC) as a guide for spatial mapping. It improves cell‐type localization, enhances sparse gene‐expression signals, and reveals CCC programs at single‐spot resolution.
Xinyi Li, Ning Zhang, Zijie Jin
wiley   +1 more source

Avaliação do efeito do meio condicionado proveniente de fibroblastos orais senescentes sobre a viabilidade e o crescimento de células de carcinoma [PDF]

TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Odontologia.O carcinoma epidermoide de boca (CEB) permanece entre as lesões malignas com maior prevalência no Brasil e no mundo, representando mais de 90% das ...
Francisconi, Nicolle da Silva
core  

Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. [PDF]

Int J Cosmet Sci
Zonari A, Brace LE, Li F, Harder NHO, Harker C, Jacob C, Kaufman J, Chilukuri S, Oliveira CR, Boroni M, Carvalho JL.   +10 more
europepmc   +1 more source

Diabetes en el senescente: definiciones, patogénesis, clínica y control

Medwave, 2001
Manuel García De los Ríos, Pilar Durruty   +1 more
openaire   +1 more source

Human Urine Stem Cells Alleviate Pulmonary Fibrosis via Inhibiting Macrophage‐Myofibroblast Transition

Advanced Science, EarlyView.
Therapeutic role and mechanism of human urine stem cells (hUSCs) in pulmonary fibrosis. hUSCs alleviated pulmonary fibrosis by selectively inhibiting macrophage‐myofibroblast transition (MMT) in two ways: on one hand, hUSCs inhibited mitochondrial reactive oxygen species (mtROS) production and apoptosis/senescence of epithelial cells in pulmonary ...
Zhou‐Hang Zhang, Guan‐Lin Guo, Xiao‐Hui Guan, Min Hu, Qi‐Ming Huang, Ding‐Wen Guo, Hao‐Cheng Gu, You‐Qiong Zhuo, Ning Li, Hong‐Bo Xin, Ke‐Yu Deng   +10 more
wiley   +1 more source

MicroRNAs and vascular damage in chronic kidney disease: advances and clinical implications. [PDF]

J Bras Nefrol
Cunha RSD, Azevedo CAB, Miniskiskosky G, Gregório PC, Stinghen AEM.   +4 more
europepmc   +1 more source