Results 71 to 80 of about 293 (222)
Liu et al. define a systems‐level interactome of fibroadipogenic progenitor (FAP)‐mediated signaling in skeletal muscle by integrating single‐cell transcriptomics with FAP depletion‐based perturbation analysis. Functional interrogation using a conditioned media bioassay links predicted signaling to multicellular outcomes, establishing a framework to ...
Xingyu Liu +13 more
wiley +1 more source
Enfermedad renal y fragilidad en pacientes geriátricos: nefropatía senescente
Grado en Nutrición Humana y ...
openaire +1 more source
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia +17 more
wiley +1 more source
O presente trabalho teve como objetivo avaliar o comportamento da cultura do sorgo submetida a doses de efluente maturado de fecularia de mandioca. Realizou-se o presente trabalho no Centro Técnico de Irrigação da Universidade Estadual de Maringá, Estado
Frederico Fonseca da Silva +4 more
doaj +1 more source
m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang +26 more
wiley +1 more source
Unveiling Lactylation: A Novel Frontier in Cancer Stemness and Therapy
Tumor metabolism and epigenetic regulation are intrinsically linked. This review highlights lactylation as a pivotal bridge connecting these processes, acting as an active epigenetic effector in cancer stemness. We delineate how lactylation orchestrates the cancer stem cell landscape and evaluate its regulatory networks.
Ting Li +9 more
wiley +1 more source
Continuando con la búsqueda de nuevos insecticidas naturales obtenidos de plantas, se estudió la actividad de un extracto de hojas senescentes (amarillas) de Melia azedarach L. (Meliaceae).
Graciela Valladares +4 more
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Decomposição in situ de folhas senescentes de pereira (Pyrus communis L. cv. Rocha)
Revista de Ciências Agrárias, vol. 30 n.º 2 (2007)
Neto,C. +4 more
openaire +2 more sources
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Factores locales y su relación con lesiones bucales en ancianos portadores de prótesis totales
Se realizó un estudio descriptivo y transversal de 96 senescentes portadores de prótesis totales, atendidos enla ClínicaEstomatológica“Lidia Doce Sánchez” de Guantánamo, desde enero de 2014 hasta abril de 2015, con vistas a determinar la relación entre ...
Marcia Hortensia Corona Carpio +4 more
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