Results 181 to 190 of about 1,556 (255)
Protective effects of Paeonia suffruticosa callus extract in skin through anti-inflammation and repair UVB-induced damage. [PDF]
Li Y +9 more
europepmc +1 more source
[Age-dependent oxidative stress: toward an irreversible failure in endothelial maintenance]. [PDF]
Thorin-Trescases N +5 more
europepmc +1 more source
This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang +10 more
wiley +1 more source
LXII Congreso Nacional de la SEHH, XXXVI Congreso Nacional de la SETH Virtual, 26-30 de octubre, 2020. [PDF]
The Authors.
europepmc +1 more source
SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Rui Long +12 more
wiley +1 more source
USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis
This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui +5 more
wiley +1 more source
EQUILÍBRIO ESTÁTICO E DINÂMICO EM INDIVÍDUOS SENESCENTES E O ÍNDICE DE MASSA CORPORAL
O estudo objetivou analisar o equilíbrio estático e o dinâmico em indivíduos senescentes e verificar sua associação com a idade e com o Índice de Massa Corporal (IMC).
José Rubens Rebelatto +3 more
core
Clinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging. [PDF]
Zonari A +10 more
europepmc +1 more source
In Situ Programmable Modulation of Hydrogel Stiffness for Stage‐Adaptive Bone Regeneration
Near‐infrared (NIR) irradiation triggers Ca2+ release from thermoresponsive nanocarriers, enabling in situ stiffening of an adaptive hydrogel from a soft to a stiff state, thereby sequentially supporting mesenchymal stromal cell stemness and osteogenic differentiation for stage‐adaptive bone regeneration.
Yuxin Yang +5 more
wiley +1 more source

