Results 81 to 90 of about 32,696 (317)
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
¿POR QUÉ ENSEÑAR GERIATRÍA DESDE EL PREGRADO?
Medicentro, 2011 El envejecimiento poblacional de la sociedad cubana es una realidad de gran interés por su tendencia al crecimiento. Cuba será, en los próximos cincuenta años, el país del Tercer Mundo más envejecido; alcanzó un 17,0 % de senescentes en el 20091.
Dr. Ángel Isern Menéndez +1 more
doaj
Produção e qualidade de híbridos de tomateiro portadores do alelo mutado dumpy [PDF]
, 2015 TCC (graduação)- Universidade Federal de Santa Catarina. Campus Curitibanos. Agronomia.Os Brassinosteróides (BRs) são um grupo de compostos esteroidais de ocorrência natural em plantas e que estão envolvidos em uma vasta gama de respostas biológicas ...
Suzuki, Joozi
core
Boletín Micológico, 2004 Se describen los aspectos morfologicos de Thozetella tocklaiensis , un raro hongo anamorfico aislado en la litera vegetal senesente de Pinus elliottii en la provincia de Misiones (Argentina), mediante el empleo de diferentes medios de cvultivo (PCA, PDA, CMA y OA), con o sin adicion de substratos vegetales tales como trozos esteriles de tallos de
Piontelli, Eduardo +1 more
openaire +3 more sources
p16-dependent increase of PD-L1 stability regulates immunosurveillance of senescent cells
Nature Cell BiologyThe accumulation of senescent cells promotes ageing and age-related diseases, but molecular mechanisms that senescent cells use to evade immune clearance and accumulate in tissues remain to be elucidated.
Julia Majewska +16 more
semanticscholar +1 more source
Hallmarks of Cellular Senescence.
Trends in Cell Biology, 2018 Cellular senescence is a permanent state of cell cycle arrest that promotes tissue remodeling during development and after injury, but can also contribute to the decline of the regenerative potential and function of tissues, to inflammation, and to ...
Alejandra Hernandez-Segura +2 more
semanticscholar +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Estudio del papel y expresión de ApoD durante la proliferación celular [PDF]
, 2017 Apolipoproteína D (ApoD) es una proteína perteneciente familia de las lipocalinas. Está presente en una gran variedad tipos celulares, principalmente células gliales del SNC, en fibroblastos perivasculares y en plasma se encuentra unida a proteínas de ...
Vaquero Cepeda, Pablo
core
The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2
Nature CancerChemotherapy often generates intratumoral senescent cancer cells that strongly modify the tumor microenvironment, favoring immunosuppression and tumor growth.
Selim Chaib +22 more
semanticscholar +1 more source
Aging and Cancer, EarlyView.Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source