Results 61 to 70 of about 970 (187)

Comparing the Efficacy of Two Drugs Senalin and Bisacodyl in Treatment of Constipation in Intensive Care Units' Patients

Advanced Biomedical Research, 2019
Background: Constipation is an intestinal syndrome that can be created alone or in the context of another disease in patients admitted to intensive care units (ICUs).
Babak Alikiaii, Mohammad Azad Majedi, Seyed Taghi Hashemi, Maryam Kiani   +3 more
doaj   +1 more source

Ciclopirox Olamine Inhibits the NLRP3 Inflammasome to Alleviate Inflammatory Diseases

Advanced Science, Volume 13, Issue 40, 17 July 2026.
There is no drug targeting the NLRP3 inflammasome that has been approved for use in clinical settings. Ciclopirox olamine (CPX), an antifungal agent approved by the US Food and Drug Administration (FDA), is identified as a specific and potent NLRP3 inflammasome inhibitor. CPX targets the NACHT domain of NLRP3 at Y381 to impair NLRP3 oligomerization and
Xinyu Xia, Hui You, Ke Zhang, Hui Jiang, Hongping Liu, Lianghua Liu, Aijie Zhang, You Zhou   +7 more
wiley   +1 more source

Kidney supportive care in Australia and New Zealand: an Australian and New Zealand Society of Nephrology (ANZSN) and Australian and New Zealand Society of Palliative Medicine (ANZSPM) guidance document

Internal Medicine Journal, Volume 56, Issue S2, Page 4-48, June 2026.
The purpose of this document is to provide a summary of the current expert opinion and recent literature for clinicians, Indigenous health workers and patient advocates interested in Kidney Supportive Care (KSC) in Australia and New Zealand. Our purpose is not to duplicate the recently released International Society of Nephrology (ISN) KSC/Conservative
Kathryn Ducharlet, Frank Brennan, Rajesh Raj, Charlotte Ogivly, Elizabeth Stallworthy, Kelly Chenlei Li, Alice Kennard, Selina Bob, Nicole Scholes‐Robertson, Riona Pais, Jenny Chen, Kirsten Hepburn, Lisa Jeffs, Ilse Berquier, Jacquelyne Hughes, Christine Sanderson, Sara Rendo, Gowri Raman, Erin Vaughan, Sarah So, Curtis Walker, Suetonia Green, Rangimarie Nadia Glavish, Mark Brown   +23 more
wiley   +1 more source

Olmesartan‐induced gastritis with no lower gastrointestinal symptoms: A case report

DEN Open, Volume 6, Issue 1, April 2026.
Abstract A 74‐year‐old man with decreased appetite, weight, and heartburn was referred to our hospital. His medications included olmesartan. Esophagogastroduodenoscopy (EGD) revealed antral‐dominant erosive gastritis and nodular mucosa. A gastric biopsy revealed inflammatory cell infiltration.
Satoshi Kosaka, Miki Kamiyama, Masahiro Ochi   +2 more
wiley   +1 more source

Involvement of Prostaglandin E-like Material in the Purgative Action of Rhein An throne, the Intraluminal Active Metabolite of Sennosides A and B in Mice [PDF]

, 1988
Intracaecal administration of rhein anthrone, the intraluminally active metabolite of sennosides A and B, to mice quickly induced severe diarrhoea. Pretreatment with the prostaglandin (PG) biosynthesis inhibitor, indomethacin, and PGE2 antagonist, SC ...
Teruyo Yagi, Kazuko Yamauchi, Yoshie Miyawaki, Shigeaki Kuwano, Tomoyo Nishikawa   +4 more
core   +1 more source

Impact of an ERAS‐Based Surgical Care Bundle Implementation for Preventing Anastomotic Leakage in Minimally Invasive Low Anterior Resection for Rectal Cancer: A Retrospective Cohort Study

World Journal of Surgery, Volume 50, Issue 3, Page 547-557, March 2026.
Anastomotic leakage (AL) remains a severe complication after low anterior resection (LAR) for rectal cancer, despite advances in minimally invasive (MI) techniques. This study aimed to evaluate the impact of a surgery‐focused care bundle, implemented on an enhanced recovery after surgery (ERAS)‐based perioperative protocol, on preventing AL and ...
Koji Tamura, Takaaki Fujimoto, Jinghui Zhang, Kinuko Nagayoshi, Yusuke Mizuuchi, Kohei Horioka, Naoki Ikenaga, Kohei Nakata, Kenoki Ohuchida, Masafumi Nakamura   +9 more
wiley   +1 more source

Preliminary non‐comparative evaluation of an adapted colonoscopy preparation protocol for dogs using sodium picosulphate and magnesium citrate

Veterinary Record, Volume 198, Issue 3, Page e101-e107, 31 January/7 February 2026.
Abstract Background Challenges associated with bowel cleansing protocols for canine colonoscopy include practical applicability and inadequate preparations. This study aimed to describe and evaluate an adapted protocol to simplify colonoscopy preparation in dogs.
Julia Elia da Silva Paranhos, Melissa Guillen Gonçalves de Souza, Daniela Araujo de Sousa, Debora Costabile Soibelman, Sabrina Martins da Costa Ferreira, Juliana da Silva Leite, Bruno Penna, Ana Maria Reis Ferreira   +7 more
wiley   +1 more source

Regular Medications Administered to Older Adults in Aged Care Facilities: A Retrospective Descriptive Study

Journal of Clinical Nursing, Volume 35, Issue 1, Page 363-374, January 2026.
ABSTRACT Aim(s) To explore which regularly prescribed medications are most commonly administered to older adults in aged care facilities in Australia, by whom and when, and to identify the prevalence of polypharmacy in this population group. Design Retrospective descriptive study.
Stephanie M. Garratt, Maneesh Prasad, Kelly Ottosen, Elizabeth Manias   +3 more
wiley   +1 more source

Comparison of the Efficacy of Polyethylene Glycol, Sennoside and Sodium Phosphate in Bowel Preparation Before Colonoscopy

Turkish Journal of Colorectal Disease, 2018
Aim: The great majority of colorectal cancers arise from pre-existing adenomatous polyps. High-quality bowel cleansing is essential to improve the quality of colonoscopy.
Emre Günay, Hasan Abuoğlu
doaj   +1 more source

Rumex Species: Phytochemistry, Pharmacology and Nutritional Potential for Food and Health Applications

Food Science &Nutrition, Volume 13, Issue 12, December 2025.
Rumex dentatus, R. vesicarius, and Emex spinosa are traditionally used for managing gastrointestinal, respiratory, hepatic, and inflammatory disorders. In addition to their ethnomedicinal value, some species are consumed as wild edibles. Pharmacological studies support their antimicrobial, antioxidant, hepatoprotective, cytotoxic, and antidiabetic ...
Mai Mohamed Gohar, Shahira Mohamed Ezzat, Balakyz Yeskaliyeva, Seham Salaheldin Elhawary, Farid Noshey Kirollos, Aya Khouchlaa, Abdelhakim Bouyahya, Daniela Calina, Javad Sharifi‐Rad, William N. Setzer, Miquel Martorell   +10 more
wiley   +1 more source