Results 51 to 60 of about 970 (187)
An in-silico approach to unravel the structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DAHPS): a critical enzyme for sennoside biosynthesis in Cassia angustifolia Vahl [PDF]
, 2023 The laxative properties of senna are attributed to the presence of sennosides produced in the plant. The low production level of sennosides in the plant is an important impediment to their growing demand and utilization.
Rushikesh Joshi (9292992) +6 more
core +1 more source
Constituents of Decoction and its Parent Herbal Medicines Determined by LC-MS/MS
Natural Product Communications, 2010 Da-Cheng-Qi decoction (DCQD) is a purgative prescription used in China and East Asia. To profile the constituents of this complex traditional Chinese medicine (TCM), a high-performance liquid chromatographic, electrospray ionization, tandem mass ...
Fengguo Xu +4 more
doaj +1 more source
RNA‐Binding Proteins: Function, Biological Mechanisms, and Therapeutic Opportunities
MedComm, Volume 7, Issue 9, September 2026.RNA‐binding proteins (RBPs) regulate RNA stability, localization, translation, and splicing through intrinsic binding domains and interactions with diverse cellular partners. Their competitive and cooperative networks shape disease‐related RNA programs, especially in cancer.
Ling Li, Xiuli Yan, Qing Ji, Hui Zhang
wiley +1 more source
Bowel Preparation for Colonoscopy in Children: 1 Day PEG-3350 with Bisacodyl versus 3 Day Sennosides [PDF]
, 2019 Background and Objectives: Bowel preparation (BP) for colonoscopy is a challenging procedure in children and different regimens have been used for this purpose. Polyethylene glycol (PEG) is the most preferred agent in recent years.
ERTEM ŞAHİNOĞLU, DENİZ +1 more
core +1 more source
Clinics, 2011 Cassia angustifolia Vahl (senna) is a natural product that contains sennosides, which are active components that affect the intestinal tract and induce diarrhea.
Deise Elizabeth Souza +5 more
doaj +1 more source
Journal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 2, Page 335-366, August 2026.Abstract Objectives Functional constipation (FC) is common in childhood, significantly impacting quality of life. Since the 2014 international guideline, new evidence has been published, and methods on making guidelines have developed. This treatment guideline for FC in children aged 0–18 years is a collaborative effort of the European and North ...
Morris Gordon +17 more
wiley +1 more source
, 2022 Insights into MD simulations of sennosides with a) 3CLpro, b) Spike-ACE2 with ligand attached at RBD, c) Spike-ACE2 with ligand attached at allosteric site, d) RdRp nsp12, and e) Helicase nsp13.
Afifa Navid (9920462) +5 more
core +1 more source
Hplc Fingerprinting Of Sennosides In Laxative Drugs With Isolation Of Standard Substances From Some Senna Leaves [PDF]
, 2011 Senna leaves are one of the oldest medicinal herbs and they are used as laxative. Herbal teas which contain senna leaves are most commonly used to promote weight loss.
Karahan, Neslihan +5 more
core +4 more sources
Effect of Sennosides on Colon Motility in Dogs [PDF]
Pharmacology, 2008 Oral administration of sennosides (20–30 mg/kg) to fasted dogs has been shown to induce a strong and long-lasting inhibition of myoelectric colon activity which was evident after a delay of 6–10 h corresponding to orocecal transit and colonic metabolism and was accompanied by abundant diarrhea.
Fioramonti, Jean +3 more
openaire +4 more sources
Functional constipation in children and young adults with Prader–Willi syndrome
JPGN Reports, Volume 7, Issue 3, Page 410-415, August 2026.Abstract Objectives Prader–Willi Syndrome (PWS) is characterized by hyperphagia, endocrinopathies, and gastrointestinal abnormalities. Clinical concerns about constipation and fecal incontinence (FI) are common, but no studies to date have clear data on functional defecation disorders in children with PWS.
Melinda J. Pierce +3 more
wiley +1 more source