Results 41 to 50 of about 970 (187)
High-Performance thin-layer chromatographic fingerprint method for the detection of sennosides in Cassia senna L. and Cassia angustifolia Vahl [PDF]
A Ph. Eur. herbal drug monograph requires for identification testing besides macroscopic (A) and microscopic (B) evaluation a thin-layer chromatography (TLC) fingerprint, prescribed as identification testing in subsection C.
Meier, Beat +7 more
core +1 more source
Dual effect of orally administered sennosides on large intestine transit and fluid absorption in the rat [PDF]
Quantity and consistency of the faecal output, large intestine transit time, and colonic net fluid absorption were investigated in rats after oral administration of sennosides A + B (12.5–200 mg kg−1). The release of normal faecal pellets was accelerated
Elke Leng-Peschlow
core +1 more source
Effect of anthraquinone derivatives on canine and rat intestinal motility. [PDF]
The effects on gastrointestinal motility of 3 senna preparations containing 18% oxidized Ca-sennosides, 60% Ca-sennosides, or pure sennosides A + B were tested in dogs and rats as measured by electromyography. Oral administration of the oxidized products
Leng-Peschlow, E +2 more
core +5 more sources
Background Mirtazapine has a good tolerability and safety profile that demonstrates several benefits over other antidepressants and it is associated with few fatalities.
Hiroki Nagasawa +5 more
doaj +1 more source
Polypharmacy among adolescents and adults with cerebral palsy in a clinical setting
Abstract Background Adolescents and adults with cerebral palsy often experience multimorbidity related to their condition, which primarily affects movement and posture but is also associated with pain, epilepsy, mood disorders, and other conditions. As such, these patients are often prescribed a range of medications to manage symptoms, thereby putting ...
Caitlin Cassidy +3 more
wiley +1 more source
The effect of sennosides on colonic mucosal histology and bowel preparation [PDF]
Introduction: A single high dose of sennosides is often used to optimize bowel preparation for diagnostic procedures. From previous studies it is suspected that sennosides in such a dose cause acute damage to the colonic mucosa.
Karrenbeld, A +3 more
core +2 more sources
Satisfactory treatment of pediatric constipation: It is time for sennosides
IntroductionA: Constipation is a condition affecting children with an estimated prevalence of 9.5–14 %, without gender differences. Its diagnosis is clinical.
Celeste Carolina Patiño Gonzalez +2 more
doaj +1 more source
Background Constipation is an underestimated but common health problem worldwide, decreasing the quality of life. Functional constipation (FC) is a common pediatric problem, with reported prevalence ranging from 0.7 to 29.6%.
Olivia Kameel Shokrey Bastaoros +4 more
doaj +1 more source
Epigenetic Regulation of Liver Fibrosis: Mechanisms and Therapeutic Implications
This review synthesizes the epigenetic mechanisms—DNA methylation, histone modifications, and non‐coding RNAs—that drive hepatic stellate cell activation and the progression of liver fibrosis. It further evaluates emerging therapeutic strategies targeting these epigenetic regulators, including DNA methyltransferase and histone deacetylase inhibitors ...
Maryam Jadid Tavaf +8 more
wiley +1 more source
ABSTRACT Background and Aims Runway time, defined as the interval between completion of polyethylene glycol ingestion and the start of colonoscopy, has been studied as a determinant of bowel cleansing quality. However, whether the bowel preparation course itself is associated with colonoscope insertion difficulty remains unclear.
Kazuki Horiuchi +2 more
wiley +1 more source

