Results 121 to 130 of about 6,140,004 (297)

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Making Sense of Business Reference A Guide for Librarians and Research Professionals

open access: yes
A detailed bibliography functions as both a standing reference for desk use as well as a collection development aid for building a core business collection.
Ross, Celia.
core  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Making Sense of Everyday Life

open access: yes, 2009
xi.236 hal.;ill.;23 ...
Scott, Susie, Susie Scott (4461160)
core  

Ethics of Sense-Making

open access: yes, 2023
In this paper, we contribute to the arising field of "enactive ethics," that is, the application of enactive cognitive science to the field of ethics. To this end, we will make a case that an "ethics of sense-making" should exist. With "sense-making," we mean the permanent everyday embodied activity of interpreting the surroundings we are in, as well ...
CANDIOTTO L, WEICHOLD M
openaire   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Making sense of oxygen sensing

open access: yesThe EMBO Journal
Homeostatic control of cellular oxygen availability is a crucial feature of all eukaryotic life, and central to this process is the ability to sense oxygen across a broad range of concentrations and time scales. Much of our understanding of the molecular
Peter J Ratcliffe, Thomas P Keeley
doaj   +1 more source

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