Results 131 to 140 of about 6,140,004 (297)

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Making Sense of Social Prescribing [PDF]

open access: yes, 2017
This report is a guide to commission, running and evaluating social prescribing ...
Polley, M.J.   +3 more
core  

Making Sense of Revolution Lost

open access: yesFrench Journal for Media Research, 2015
Ce document vise à identifier les discours et les comportements au sein de la presse écrite en Afrique du Sud dans son rapport général sur la transition au pouvoir en compétition par le nouveau Congrès national africain (ANC) -LED gouvernement à la suite
Tomaselli P. Eric Louw and Keyan G.
doaj  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Sense-T: Sensor smart irrigation

open access: yes, 2017
The Sense-T Sensor-Smart Irrigation app predicts daily soil-water in the infield spatial zones using FAO-56. The irrigation requirement is determined in each zone from the difference between the predicted soil-water and field capacity. Incorporation of a
McCarthy, Alison   +2 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

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