Results 161 to 170 of about 822,405 (289)

Gravity beyond starch: molecular evidence for a parallel gravity sensing mechanism. [PDF]

Plant Physiol
McNelly R, Depaepe T.
europepmc   +1 more source

Expanding role of deoxyribonucleic acid-sensing mechanism in the development of lifestyle-related diseases. [PDF]

Front Cardiovasc Med, 2022
Nishimoto S, Sata M, Fukuda D.
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

The Role of Quorum Sensing Mechanism in the Functional Properties of Lactic Acid Bacteria. [PDF]

Microorganisms
Iodice A, Tommonaro G.
europepmc   +1 more source

Simulation of the sensing mechanism in quantum dot gas sensor by quantum light harvesting approach. [PDF]

Front Chem, 2022
Suntijitrungruang O, Lakronwat J, Uthailiang T, Pongkitiwanichakul P, Boonchui S.   +4 more
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Fluidic Response and Sensing Mechanism of Meissner's Corpuscles to Low-Frequency Mechanical Stimulation. [PDF]

Sensors (Basel)
Chen S, Yuan T, Yang Z, Ru W, Yang N.
europepmc   +1 more source

Study on Sensing Mechanism of Volatile Organic Compounds Using Pt-Loaded ZnO Nanocrystals. [PDF]

Sensors (Basel), 2022
Shinkai T, Masumoto K, Iwai M, Inomata Y, Kida T.   +4 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

A Noncanonical Auxin-Sensing Mechanism Uncovered by Screening the Auxin Response Factor 3 Interacting Proteins in Tomato. [PDF]

Int J Mol Sci
Wang L, Yang X, Muntha S, Dong L, Xie Q, Wang T, Shi C, Yang C.   +7 more
europepmc   +1 more source