Results 111 to 120 of about 4,715,263 (253)

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

A simple way of improving the Bar–Lev, Bobovitch and Boukai Randomized response model

Kuwait Journal of Science, 2017
Eichhorn & Hayre (1983) considered a randomized response procedure suitable for estimating the mean response, when the sensitive variable under investigation is quantitative in nature.
Tanveer A. Tarray, Housila P. Singh
doaj  

A Sensitive SERS Sensor Combined with Intelligent Variable Selection Models for Detecting Chlorpyrifos Residue in Tea

Foods
Chlorpyrifos is one of the most widely used broad-spectrum insecticides in agriculture. Given its potential toxicity and residue in food (e.g., tea), establishing a rapid and reliable method for the determination of chlorpyrifos residue is crucial.
Hanhua Yang, Hao Qian, Yi Xu, Xiaodong Zhai, Jiaji Zhu   +4 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Experimental demonstration of high-speed continuous variable quantum key distribution enhanced by phase-sensitive amplifier

npj Quantum Information
The type of system employing continuous variables, such as light field quadrature for signal modulation, is an important branch for quantum key distribution.
Jinpeng Liao, Zhirong Chen, Jintao Wang, Hao Xiao, Xiaojie Guo, Zhaohui Li, Dawei Wang   +6 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Continuous-variable quantum key distribution over multispan links employing phase-insensitive and phase-sensitive amplifiers

New Journal of Physics
Transmission losses through optical fibers are one of the main obstacles preventing both long-distance quantum communications and continuous-variable quantum key distribution.
M N Notarnicola, F Cieciuch, M Jarzyna
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Phase sensitive amplification in a highly nonlinear lead-silicate fibre

We experimentally demonstrate phase-sensitive amplification in a highly nonlinear lead-silicate W-type fibre. A phase-sensitive gain swing of 6dB was observed in a 1.56m sample of the fibre for a total launched power of ...
Shi, J.D., Petropoulos, P., Richardson, D.J., Poletti, F., Kakande, J., Loh, W.H., Ettabib, M.A., Petrovich, M.N., Ponzo, G.M., Jones, L., Slavík, R., Parmigiani, F., Feng, X.   +12 more
core   +1 more source