Results 111 to 120 of about 5,431,305 (239)

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

تمییز المظاهر الأرضیة باستخدام التحویل المویجی

Al-Rafidain Journal of Computer Sciences and Mathematics, 2009
Faten A. Mustafa, Turkan A. Khalil, Almas A. Khalil   +2 more
doaj   +1 more source

Evaluation of the Human Immunodeficiency Virus viral load surveillance system, national perspective in Tanzania: A descriptive cross-sectional study

Journal of Interventional Epidemiology and Public Health
Introduction: Human immunodeficiency virus (HIV) infection is still a global public health problem. The number of HIV-positive individuals was estimated to be 38.0 million worldwide in 2020, with 2.78 million being children and adolescents aged 0 to 19 ...
Peter Richard Torokaa, Loveness John Urio, Ambwene Mwakalobo, Alex Sifaeli Magesa, James Njoroge Allan, David John Osima, Focus Medard Shao, Joseph Mziray, Yulitha Barnabas, Agricola Joachim, Mtebe Majigo   +10 more
doaj   +1 more source

Moral Sensitivity: A Comparative Analysis of Undergraduate and Graduate Nursing Students [PDF]

, 2015
This study examined the relationship of undergraduate and graduate-level nursing student self-reported moral sensitivity and social desirability.
Bishop, Rhonda
core  

Sense and Sensitivity

, 2021
Sense and Sensitivity celebrates the unique sensorial place of autistic artistry in the world via the lens of autistic landscape photographer, Simon Phillips, and the deep listening of autistic performance artist Dawn-joy Leong.
Leong, Dawn-joy, D'Arcy, Emily, Girdler, Sonya, Phillips, Simon, Ellis, Katie, Fyfe, Jordan   +5 more
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Widespread Sensitivity of Grassland Water Use Efficiency to Deep Soil Moisture on the Tibetan Plateau

Water Resources Research
Water use efficiency (WUE, the ratio of gross primary productivity to evapotranspiration (ET)) is a robust indicator of ecosystem response to climate change, with soil moisture serving as a crucial determinant. Soil moisture varies across soil layers due
Yang Liu, Cheng Chen, Qiuwen Chen, Jianyun Zhang, Zhen Cui, Zhenzhong Zeng   +5 more
doaj   +1 more source

Converters' Loading Balance and Stability Verification for Doubly-Fed Induction Generators

CSEE Journal of Power and Energy Systems
Back-to-back converters are the main components of a doubly-fed induction generator (DFIG). If the loadings of the rotor-side converter (RSC) and the grid-side converter (GSC) are balanced, the capacity and the cost of the DFIG will be reduced.
Shenghu Li
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Extended Sensitivity Analysis for Applied General Equilibrium Models [PDF]

Previous sensitivity analysis procedures for applied general equilibrium models have focussed on the values of exogenously assigned elasticity parameters, while the calibrated parameters -those that are obtained from combining elasticity information with
Christina Dawkins
core