Insulin secretion, insulin sensitivity, and glucose effectiveness in nonobese individuals with varying degrees of glucose tolerance. [PDF]
, 2000 A Taniguchi +7 more
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Counterfactual Sensitivity and Robustness
, 2019 Researchers frequently make parametric assumptions about the distribution of unobservables when formulating structural models. Such assumptions are typically motived by computational convenience rather than economic theory and are often untestable ...
Christensen, Timothy, Connault, Benjamin
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
A Noise-Sensitivity-Analysis-Based Test Prioritization Technique for Deep Neural Networks [PDF]
, 2019 Long Zhang +3 more
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LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Frontiers in Nuclear MedicineBackground18F-FDG-PET/CT may reveal widespread inflammation of musculoskeletal structures in polymyalgia rheumatica (PMR). Currently, scans are subjectively analysed based on the overall gestalt of the scan.
Kornelis S. M. van der Geest +7 more
doaj +1 more source
Sensitivity versus Certificate Complexity of Boolean Functions [PDF]
, 2015 Andris Ambainis +2 more
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Review of: "Antimicrobial Sensitivity of Plant Extracts of Acacia arabica, Prosopis juliflora, Abutilon indicum, and Bryonia laciniosa on Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli" [PDF]
, 2023 Iliana Barrera‐Martínez
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