Results 81 to 90 of about 5,431,305 (239)

In Vitro Assessment of Penicillium expansum Sensitivity to Difenoconazole

Microorganisms
Penicillium expansum causes blue mold, a major post-harvest disease affecting apples. This disease is commonly managed using fungicides, including Difenoconazole (Dif), a demethylation inhibitor (DMI) approved for its control.
Mohammed Khadiri, Hassan Boubaker, Abdelaaziz Farhaoui, Said Ezrari, Mohammed Radi, Rachid Ezzouggari, Fouad Mokrini, Essaid Ait Barka, Rachid Lahlali   +8 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

The Subjective Visual Vertical and Electrocochleography Tests in Individuals with Meniere's Disease [PDF]

Iranian Journal of Otorhinolaryngology
Introduction: Meniere's disease is an inner ear disorder not associated with central brain structure involvement. Although the ECochG test has been commonly used to diagnose Meniere's disease recently, it has not demonstrated high sensitivity. Therefore,
Hadi Behzad, Reza Gharibi, Mahmood RezvaniAmin, Setareh Kafashan, Ali Kamrani   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Vulnerability of maize, barley, and wheat yields to growing season temperature and socioeconomic indicators in Morocco

Journal of Water and Climate Change
In Morocco, the historical record depicts a situation characterized by increasing temperatures and diminishing precipitation, which often ends up in severe drought episodes.
Soumia Achli, Terence Epule Epule, Driss Dhiba, Wiam Salih, Abdelghani Chehbouni   +4 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

18F-FDG-PET/CT for polymyalgia rheumatica: agreement and diagnostic accuracy of routine PET scan report vs. standardized PMR PET scores

Frontiers in Nuclear Medicine
Background18F-FDG-PET/CT may reveal widespread inflammation of musculoskeletal structures in polymyalgia rheumatica (PMR). Currently, scans are subjectively analysed based on the overall gestalt of the scan.
Kornelis S. M. van der Geest, Rob G. J. Grootelaar, Karin Bouwman, Maria Sandovici, Andor W. J. M. Glaudemans, Elisabeth Brouwer, Riemer H. J. A. Slart, Riemer H. J. A. Slart   +7 more
doaj   +1 more source

Event tracking for real-time unaware sensitivity analysis (EventTracker) [PDF]

, 2013
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2013 IEEE. Personal use of this material is permitted.
Broomhead, P, Tavakoli, S, S. Tavakoli, A. Mousavi, Mousavi, A, P. Broomhead   +5 more
core   +1 more source