Results 61 to 70 of about 8,396,703 (346)

Maturity Onset Diabetes of the Young (MODY): French National Diagnosis and Care Protocol (PNDS, Protocole National de Diagnostic et de Soins)

Orphanet Journal of Rare Diseases
MODY (Maturity-Onset Diabetes of the Young) is characterized by autosomal dominant mode of inheritance, early onset of diabetes in the absence of autoimmunity directed to pancreatic β-cells, impaired insulin secretory capacity, however, maintained over ...
Danièle Dubois-Laforgue, Bruno Donadille, Cécile Ciangura , Chloé Amouyal, Jean-Baptiste Arnoux, Pascal Barat, Sabine Baron, Jacques Beltrand, Elise Bismuth, Clara Bouché, Jean-Claude Carel, Hélène Cavé, Sophie Christin-Maitre, Delphine Collin-Chavagnac, Christiane Damgé, Brigitte Delemer, Pierre Gourdy , Sophie Jacqueminet, Sonja Janmaat , Marc de Kerdanet, Laurence Kessler, Dominique Langin , Jean-Charles Nault, Jacky Nizard, Michel Polak , Rachel Reynaud, Cécile Saint-Martin, Igor Tauveron, René Valéro, Anne Vambergue, Marie-Christine Vantyghem, Camille Vatier, Marc Nicolino, Christine Bellanné-Chantelot, Corinne Vigouroux   +34 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

A Nanoparticle, Fluorescence-Based Rinse for Caries Activity Assessment, an in Vitro Study

International Dental Journal
Objectives: This in vitro study aimed to compare the agreement of a starch-based nanoparticle fluorescence rinse (FR) (LumiCare™ Caries Detection Rinse, GreenMark Biomedical Inc.) in the assessment of caries activity of initial smooth surface carious ...
Bruna Leticia Vessoni Menoncin, Wendy Bloembergen, Nathan Jones, Adam Hoxie, Matthew Finkelman, Andrea Ferreira Zandona   +5 more
doaj   +1 more source

Size of Sets with Small Sensitivity: a Generalization of Simon's Lemma

, 2016
We study the structure of sets $S\subseteq\{0, 1\}^n$ with small sensitivity. The well-known Simon's lemma says that any $S\subseteq\{0, 1\}^n$ of sensitivity $s$ must be of size at least $2^{n-s}$. This result has been useful for proving lower bounds on
Ambainis, Andris, Vihrovs, Jevgēnijs
core   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

A Comparison of Contrast-Enhanced Voiding Urosonography (CE-VUS) and Contrast Retrograde Cystourethrography (RCUG) for the Detection of Vesicoureteral Reflux in Young Dogs

Animals
The aim of this prospective study was to evaluate contrast-enhanced urosonography (CE-VUS) as an alternative to radiographic retrograde cystourethrography (RCUG) in the detection of vesicoureteral reflux (VUR) in young dogs.
Georgia Trikoupi, Paraskevi Papadopoulou, Katerina K. Adamama-Moraitou, Maria Eleni Filippitzi, Savvas Deftereos, Christos Koutinas, Michail Patsikas, Frederica Papadopoulou   +7 more
doaj   +1 more source

The effect of antimicrobial agents on planktonic and biofilm forms of bacteria that are isolated from chronic anal fissures

Regulatory Mechanisms in Biosystems, 2017
The microorganisms that are formed in biofilm cause about 60% of chronic and recurrent diseases, and as a consequence, traditional etiotropic antibacterial therapy is ineffective.
I. M. Kozlovska, N. Y. Romanjuk, L. M. Romanjuk, M. D. Kukhtyn, Y. V. Horiuk, G. V. Karpyk   +5 more
doaj   +1 more source

Sensitivity to the initial conditions of the Time-Dependent Density Functional Theory [PDF]

, 2021
Aurel Bulgac, Ibrahim Abdurrahman, Gabriel Wlazłowski   +2 more
openalex   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source