Results 51 to 60 of about 4,655,855 (296)

Sensitivity analysis of risk assessment for continuous Markov process Monte Carlo method using correlated sampling method [PDF]

, 2023
The correlated sampling method is applied to the continuous Markov-chain Monte-Carlo (CMMC) method to efficiently perform sensitivity analysis of input parameters such as the failure rate of safety components.
Endo, Tomohiro, Morishita, Yuki, Yamamoto, Akio   +2 more
core   +1 more source

Killing Glioblastoma Cells with Glycosylated Indolocarbazole-Based Derivative LCS1269: A Potential Crosstalk Between Micronuclei Formation and the Concurrent Induction of Apoptosis, Necroptosis, and Pyroptosis

Pharmaceuticals
Background/Objectives: Glioblastoma multiforme (GBM) is the most infiltrative, treatment-resistant, and deadly brain tumor in adults. Given the extremely malignant phenotype of the GBM cells, the high intratumoral heterogeneity, and the limited efficacy ...
Nikolay Kalitin, Alexander Masyutin, Maria Erokhina, Ekaterina Savchenko, Nadezhda Samoylenkova, Aida Karamysheva, Galina Pavlova   +6 more
doaj   +1 more source

Mannitol Sensitivity [PDF]

Journal of Bacteriology, 1972
The addition of mannitol to cultures of Salmonella typhimurium mutants missing mannitol-1-phosphate dehydrogenase causes stasis or lysis. Mannitol-1-phosphate accumulates intracellularly to concentrations of 20 m m .
P, Jensen, C, Parkes, D, Berkowitz
openaire   +2 more sources

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source

Evaluation of dry-in-place lubricants for cold forging by using an optimal steady combined forward and backward extrusion testing method

Friction, 2023
This study evaluated dry-in-place lubricants used for cold forging. A group of isothermal compression tests with a strain rate ( $$\dot \varepsilon $$ ε ˙ ) range of 0.001–1 s−1 and temperature (T) range of 30–400 °C were completed.
Chengliang Hu, Shogo Osaki, Baixuan Cai, Mitsuru Aoyama, Kuniaki Dohda   +4 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Study on PCR rapid molecular detection technique of Meloidogyne vitis

Journal of Integrative Agriculture, 2022
Meloidogyne vitis is a new root-knot nematode parasitic on grape root in Yunnan Province, China. In order to establish a rapid, reliable and specific molecular detection method for M.
Yan-mei YANG, Pei LIU, Hong-mei LI, Huan PENG, Xia DU, Ye DONG, Xian-qi HU   +6 more
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

alk-collateral-sensitivity v1.0

, 2016
Repository for the R code and experimental data for the paper "Collateral sensitivity networks reveal evolutionary instability and novel treatment strategies in ALK mutated non-small-cell lung cancer." (preprint available ...
andrewdhawan
core   +1 more source