Results 91 to 100 of about 8,396,703 (346)

A Comparison of the Sensitivity and Cellular Detection Capabilities of Magnetic Particle Imaging and Bioluminescence Imaging

open access: yesTomography
Background: Preclinical cell tracking is enhanced with a multimodal imaging approach. Bioluminescence imaging (BLI) is a highly sensitive optical modality that relies on engineering cells to constitutively express a luciferase gene.
Sophia Trozzo   +2 more
doaj   +1 more source

Sensitivity Analysis

open access: yes, 2018
Cross-cultural analysis is all about comparing groups. Whether the groups being compared are countries, ethnicities, religions, or scientific fields, the goal is always to assess whether these groups differ in some respect and to interpret those differences in substantive terms.
openaire   +2 more sources

Domain-sensitivity

open access: yesSynthese, 2010
In this paper, I argue that there are good motivations for a relativist account of the domain-sensitivity of quantifier phrases. I will frame the problem as a puzzle involving what looks like a logically valid inference, yet one whose premises are true while the conclusion is false. After discussing some existing accounts, literalist and contextualist,
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

In Vitro Assessment of Penicillium expansum Sensitivity to Difenoconazole

open access: yesMicroorganisms
Penicillium expansum causes blue mold, a major post-harvest disease affecting apples. This disease is commonly managed using fungicides, including Difenoconazole (Dif), a demethylation inhibitor (DMI) approved for its control.
Mohammed Khadiri   +8 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The Subjective Visual Vertical and Electrocochleography Tests in Individuals with Meniere's Disease [PDF]

open access: yesIranian Journal of Otorhinolaryngology
Introduction: Meniere's disease is an inner ear disorder not associated with central brain structure involvement. Although the ECochG test has been commonly used to diagnose Meniere's disease recently, it has not demonstrated high sensitivity. Therefore,
Hadi Behzad   +4 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Vulnerability of maize, barley, and wheat yields to growing season temperature and socioeconomic indicators in Morocco

open access: yesJournal of Water and Climate Change
In Morocco, the historical record depicts a situation characterized by increasing temperatures and diminishing precipitation, which often ends up in severe drought episodes.
Soumia Achli   +4 more
doaj   +1 more source

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