Results 131 to 140 of about 8,147,464 (347)

Noise sensitivity in bootstrap percolation

, 2015
Answering questions of Itai Benjamini, we show that the event of complete occupation in 2-neighbour bootstrap percolation on the d-dimensional box [n]^d, for d\geq 2, at its critical initial density p_c(n), is noise sensitive, while in k-neighbour ...
Bartha, Zsolt, Pete, Gábor
core  

Sensitivity Analysis

, 2018
Cross-cultural analysis is all about comparing groups. Whether the groups being compared are countries, ethnicities, religions, or scientific fields, the goal is always to assess whether these groups differ in some respect and to interpret those differences in substantive terms.
openaire   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Geometric sensitivity of modal parameters in wind instrument models: a case study on saxophone intonation

Acta Acustica
The Transfer Matrix Method is a practical approach for modeling plane wave propagation in one-dimensional waveguides. Its simplicity makes it especially attractive for accounting for viscothermal losses, enabling realistic simulations of complex ...
Szwarcberg Nathan, Colinot Tom, Vergez Christophe, Jousserand Michaël   +3 more
doaj   +1 more source

The uniform general signed rank test and its design sensitivity

, 2019
A sensitivity analysis in an observational study tests whether the qualitative conclusions of an analysis would change if we were to allow for the possibility of limited bias due to confounding.
Howard, Steven R., Pimentel, Samuel D.
core  

NTRK kinase domain mutations in cancer variably impact sensitivity to type I and type II inhibitors

, 2020
Romel Somwar, Nicolle E. Hofmann, Bryan D. Smith, Igor Odintsov, Morana Vojnic, Irina Linkov, Ashley Tam, Inna Khodos, Marissa S. Mattar, Elisa de Stanchina, Daniel L. Flynn, Marc Ladanyi, Alexander Drilon, Ujwal Shinde, Monika A. Davare   +14 more
openalex   +1 more source

Does size really matter? A sensitivity analysis of number of seeds in a respondent-driven sampling study of gay, bisexual and other men who have sex with men in Vancouver, Canada [PDF]

, 2016
Nathan J. Lachowsky, Justin Sorge, H. Fisher Raymond, Zishan Cui, Paul Sereda, Ashleigh J. Rich, Eric Abella Roth, Robert S. Hogg, David Moore   +8 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Efficient Cataluminescence Sensor for Detecting Methanol Based on NiCo₂O₄//MIL-Ti₁₂₅ Polyhedral Composite Nano-Materials

Chemosensors
Since methanol has a significant health hazard due to its inherent toxicity, it is urgent to develop a method capable of rapid, sensitive, and continuous monitoring of methanol.
Hongyan Wang, Ziyu Shao, Mao Cai, Guoji Shi, Bai Sun   +4 more
doaj   +1 more source