Results 41 to 50 of about 8,147,464 (347)

Enhancing ELISA Sensitivity: From Surface Engineering to Synthetic Biology

open access: yesBiosensors
Accurate and sensitive detection of protein biomarkers is critical for advancing in vitro diagnostics (IVD), yet conventional enzyme-linked immunosorbent assays (ELISA) often fall short in terms of sensitivity compared to nucleic acid-based tests ...
Hye-Bin Jeon   +3 more
doaj   +1 more source

Visual sensitivity tester [PDF]

open access: yes, 1972
Testing device uses closed loop film cassettes to project programmed visual stimuli on screen which the observer views through a lens making the stimuli appear to be at optical infinity.
Fitzgerald, J. W.   +2 more
core   +1 more source

Sensitivity Analysis of Flexible Provisioning

open access: yes, 2007
This technical report contains a sensitivity analysis to extend our previous work. We show that our flexible service provisioning strategy is robust to inaccurate performance information (when the available information is within 10% of the true value ...
Jennings, N. R.   +2 more
core   +1 more source

Evolving Sensitivity [PDF]

open access: yesACS Chemical Biology, 2006
Engineering gene circuits with novel functions holds promise for broad applications in biology, engineering, and medicine. Directed evolution complements rational design as an important strategy for optimizing gene circuits and circuit elements.
Hao, Song, Lingchong, You
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

EVALUATION OF DIPHTHERIA SURVEILLANCE SYSTEM IN PROBOLINGGO DISTRICT: STUDY OF SYSTEM APPROACH AND ATTRIBUTES

open access: yesJurnal Berkala Epidemiologi
Background: There is still an outbreak of diphtheria in the Probolinggo district in 2023. Diphtheria mainly affects children who are not immunized. Support through a surveillance system is needed to overcome the diphtheria problem.
Lidya Nur Maulina   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

New Uses for Sensitivity Analysis: How Different Movement Tasks Effect Limb Model Parameter Sensitivity [PDF]

open access: yes, 1984
Original results for a newly developed eight-order nonlinear limb antagonistic muscle model of elbow flexion and extension are presented. A wider variety of sensitivity analysis techniques are used and a systematic protocol is established that shows how ...
Stark, L., Winters, J. M.
core   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

open access: yesFEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji   +3 more
wiley   +1 more source

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