Results 91 to 100 of about 2,651,129 (312)

D2PC sensitivity analysis [PDF]

, 1992
The Chemical Hazard Prediction Model (D2PC) developed by the US Army will play a critical role in the Chemical Stockpile Emergency Preparedness Program by predicting chemical agent transport and dispersion through the atmosphere after an accidental release. To aid in the analysis of the output calculated by D2PC, this sensitivity analysis was conducted
openaire   +3 more sources

Incomplete Data in Clinical Studies: Analysis, Sensitivity, and Sensitivity Analysis [PDF]

Drug Information Journal, 2009
Statistical analysis often extends beyond the data available. This is especially true when data are incompletely recorded because ad hoc as well as model-based approaches are rooted not only in the observed data and the mechanism governing missingness, but also in the unobserved given the observed data.
openaire   +3 more sources

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

Experimental Sensitivity Data for Radioactivation Analysis with 14 MeV. Neutrons [PDF]

, 1963
Yuzuru KUSAKA, Haruo Tsuji, Takayoshi Adachi   +2 more
openalex   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Development and Application of a Sensitivity and Uncertainty Analysis Framework for Safety Analysis of Molten Salt Reactors

Energies
To provide reliable safety margins in reactor design and safety analysis, the best estimate plus uncertainty (BEPU) analysis, which is recommended by the International Atomic Energy Agency (IAEA), has drawn increasing attention worldwide.
Haijun Liu, Rui Li, Xiandi Zuo, Maosong Cheng, Shichao Chen, Zhimin Dai   +5 more
doaj   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Increased Sensitivity of Ethylenediamine Analysis for Norepinephrine [PDF]

, 1962
Herbert Sheppard, JOSEPH H. ZIMMERMAN
openalex   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Assessing the Sensitivity of Snow Depth Simulations to Land Surface Parameterizations within Noah-MP in Northern Xinjiang, China

Remote Sensing
Snow cover plays a crucial role in the surface energy balance and hydrology and serves as a key indicator of climate change. In this study, we conducted an ensemble simulation comprising 48 members generated by randomly combining the parameterizations of
Yuanhong You, Chunlin Huang, Yuhao Zhang
doaj   +1 more source