Results 91 to 100 of about 3,327,512 (288)

Extended Sensitivity Analysis for Applied General Equilibrium Models [PDF]

open access: yes
Previous sensitivity analysis procedures for applied general equilibrium models have focussed on the values of exogenously assigned elasticity parameters, while the calibrated parameters -those that are obtained from combining elasticity information with
Christina Dawkins
core  

Characterization of process-oriented hydrologic model behavior with temporal sensitivity analysis for flash floods in Mediterranean catchments [PDF]

open access: yes, 2013
This paper presents a detailed analysis of 10 flash flood events in the Mediterranean region using the distributed hydrological model MARINE. Characterizing catchment response during flash flood events may provide new and valuable insight into the ...
Dartus, Denis   +9 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

An application of global sensitivity analysis in evaluation of transmission line fault-locating algorithms

open access: yes, 2010
Computation of distance to fault on an electrical transmission line is affected by many sources of uncertainty, including parameter setting errors, measurement errors, as well as absence of information and incomplete modelling of a system under fault ...
Zivanovic, R.   +2 more
core   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

Automated Sensitivity Analysis in Early Space Mission Design

open access: yes, 2012
Concurrent Engineering in space mission design features several hundred design parameters provided by more than a dozen domain experts. The quality of the design strongly depends on the individual expertise of the people in the team, their experience and
Schaus, Volker   +3 more
core  

Global sensitivity analysis of an end-to-end marine ecosystem model of the North Sea : factors affecting the biomass of fish and benthos [PDF]

open access: yes, 2014
Comprehensive analysis of parameter and driver sensitivity is key to establishing the credibility of models of complex systems. This is especially so for models of natural systems where experimental manipulation of the real-world to provide controlled ...
Speirs, Douglas   +7 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Climate variability from annual to multi-decadal timescales in a two-layer stochastic energy balance model: analytic solutions and implications for general circulation models

open access: yesTellus: Series A, Dynamic Meteorology and Oceanography, 2019
A low-order stochastically forced two-layer global energy balance model (EBM) admitting an analytical solution is developed for studying natural inter-annual, decadal and multi-decadal climate variability, and ultimately to better understand forced ...
Sergei Soldatenko, Robert Colman
doaj   +1 more source

Appendix C Sensitivity of Stochastic Models Hansen, T. M. and Singh, S, April 1997

open access: yes, 2007
Contents C Sensitivity Analysis of Stochastic Models of the Crust 1 C.1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 C.2 Fractal Nature of the Crust . . . . . . . . . . . . . . . . . . . . . . . . . . .
Sensitivity Of Stochastic
core  

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