Results 231 to 240 of about 2,595,666 (406)

The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity

Molecular Oncology, EarlyView.
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause, Rixa‐Mareike Köhn, Christian Ickes, Julia Lenger, Jonas Fischer, Sabrina Cappello, Ivan Bogeski   +6 more
wiley   +1 more source

Sensitivity and Specificity of Natural Language Processing Systems for Identification of Hospitalized People Who Use Drugs. [PDF]

Open Forum Infect Dis
Benrubi L, Sato T, Westgard LK, Zollo-Venecek K, Socrates B, Sweigart B, Ridgway JP, Suzuki J, Morales Y, Goodman-Meza D, Wurcel AG.   +10 more
europepmc   +1 more source

Sensitivity and specificity in tests of distal ileal function: prospective comparison of bile acid and vitamin B 12 absorption in ileal resection patients.

, 1973
Hans Fromm, Paul J. Thomas, Alan F. Hofmann   +2 more
openalex  

The sensitivity, specificity and efficiency values of some serological tests used in the diagnosis of paracoccidioidomycosis [PDF]

, 1991
Gilda Maria Bárbaro Del Negro, Nilma Maciel Garcia, Elaine G. Rodrigues, Maria Isabel Nogueira Cano, Mônica S.M.V. de Aguiar, Vanda de Sá Lírio, Carlos da Silva Lacaz   +6 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Definition of sensitivity and specificity [PDF]

The American Journal of Clinical Nutrition, 1999
openaire   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Brief Diagnostic Criteria for Temporomandibular Disorders: Sensitivity and Specificity of Clinical Diagnoses (A Multi-Center Study). [PDF]

J Oral Rehabil
Nykänen L, Sipilä K, Eli I, Freidman-Rubin P, Keren L, Kämppi A, Näpänkangas R, Tamar SA, Tanner J, Teerijoki-Oksa T, Winocur E, Emodi-Perlman A.   +11 more
europepmc   +1 more source

Sensitivity Analysis for a Specific Fusion Reactor Shielding Experiment Containing Tungsten

, 1983
R. G. Alsmiller, R. T. Santoro, R.L. Childs, J. M. Barnes, J.L. Lucius   +4 more
openalex   +2 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source