Results 51 to 60 of about 1,129,627 (263)
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
The CERES-Rice (V4.7.5) model was used to identify the optimum transplanting window for higher productivity of rice in Indian Punjab. The model was first sensitized for 11 genetic coefficients and then these values were used for calibrating and ...
Anupama Aryal +3 more
doaj +1 more source
The increase in the scale of distribution networks significantly reduces the efficiency of intelligent planning for distributed generation (DG). To improve the efficiency of intelligent DG planning and avoid the impact of uncertainty concerning renewable
Dawei Huang +5 more
doaj +1 more source
The new cystometric index — index of bladder sensitivity
Our analysis of the results of urodynamic studies in 341 patients with overactive bladder showed the possibility of using the new urodynamic index — the index of bladder sensitivity (IBS). IBS is calculated as the ratio of the maximal bladder capacity to bladder volume at the time of first desire to urinate. IBS values depend on the sex of the patient,
Salman Hasunovich Al-Shukri +1 more
openaire +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Application of the consciousness index (IoC1) combined with injury sensitive index (IoC2) in cesarean section under general anesthesia [PDF]
Objective To investigate the application of the consciousness index 1(IoC1) combined with injury sensitive index 2(IoC2) in cesarean section under general anesthesia.
YUAN Bao-hong, LIU Xiao-nan
doaj

