Results 71 to 80 of about 1,129,627 (263)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

An Efficient Solution for Probabilistic Slope Seismic Stability Analysis Based on Polynomial Chao Kriging Metamodel

GeoHazards
Slope stability analysis plays a crucial role in geotechnical engineering, particularly in regions susceptible to seismic activity. The inherent non-homogeneity and uncertainty of soil properties pose significant challenges in assessing slope stability ...
Tingting Zhang, Daniel Dias
doaj   +1 more source

Insulin sensitivity index (ISI 0-120) from oral glucose tolerance test in healthy young adults

National Journal of Physiology, Pharmacy and Pharmacology, 2017
Background: Insulin sensitivity (IS) is the body’s systemic responsiveness to glucose and it is the measure of the ability of endogenous insulin to reduce the glucose in extracellular fluids by inhibition of gluconeogenesis and increase peripheral ...
Preethi Bangalore Lakshmanagowda, Prasanna Kumar K M, Jayshree G   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Estimation of soybean crop water deficit sensitivity index [PDF]

Scientia Agricola
Brazil is the world’s largest soybean exporter. Over half of the cultivated area is in the Brazilian Savanna (Cerrado) region, where soybean is typically grown under rainfed conditions. However, soybeans have been cultivated in irrigated systems, further
Diego Bispo dos Santos Farias, Lineu Neiva Rodrigues, Catariny Cabral Aleman, Paulo Roberto Cecon   +3 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Theoretical and numerical approach for quantifying sensitivity to system parameters of nonlinear systems

Nonlinear Engineering
Sensitivity evaluation of nonlinear systems to system parameters is critically important in nonlinear dynamics, though current focuses in the field are mainly on the sensitive dependence of nonlinear systems upon initial conditions.
Xia Dandan, Dai Liming
doaj   +1 more source

Application of Extrapolation Capability of Vector Fitting for Out-of-Band Dominant Modal Synthesis of Voltage-Source Converters

IEEE Open Access Journal of Power and Energy
Conventional state-space-based stability assessment method of voltage-source converters (VSCs) can be hindered by the black-box feature. Black box-based state-space model identification method using the terminal admittance/impedance frequency responses ...
Weihua Zhou, Jef Beerten
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Local refractive index sensitivity of plasmonic nanoparticles

Optics Express, 2011
We report on an experimental characterization of the sensitivity of localized surface plasmons (LSP) to local changes in the refractive index at a nanometer scale. The method is based on forming a polymer mask covering different well defined areas of metallic nanoparticles and measuring the extinction peak shifts associated with the local refractive ...
Piliarik, M. (Marek), Kvasnička, P. (Pavel), Galler, N., Krenn, J. R., Homola, J. (Jiří)   +4 more
openaire   +3 more sources