Results 71 to 80 of about 6,464,851 (305)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Uncertainty and Sensitivity Analysis of the Human Development Index [PDF]
This paper discusses the methodological judgments made during the development of the Human Development Index (HDI), and analyzes the quantitative and qualitative impact of different methodological choices on the HDI scores, as well as on the associated ...
Clara García Aguña, Milorad Kovacevic
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The 2005 European e-Business Readiness Index [PDF]
Assessment of the eEurope 2005 Action Plan Benchmarking Index “E-Business Readiness Composite Indicator” using data collected by National Statistical Institutes and harmonised by Eurostat, using surveys “ICT usage of enterprises”, with reference years ...
Pennoni, Fulvia +2 more
core
, 2008 Excel files of bispectral index (BIS), anaesthesia levels and nominal patient data based on sensitivity to ...
Abdulla, Shahab
core +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Yield, quality and drought sensitivity of tomato to water deficit during different growth stages
Scientia AgricolaIn areas where the supply of water for irrigation is limited, tomato production is often subject to drought stress. In order to investigate the drought sensitivity of tomato (Lycopersicon esculentum Mill.) yield and quality during different growth stages,
Jintao Cui +4 more
doaj +1 more source
Application of the consciousness index (IoC1) combined with injury sensitive index (IoC2) in cesarean section under general anesthesia [PDF]
Jichu yixue yu linchuang, 2021 Objective To investigate the application of the consciousness index 1(IoC1) combined with injury sensitive index 2(IoC2) in cesarean section under general anesthesia.
YUAN Bao-hong, LIU Xiao-nan
doaj
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source