Results 81 to 90 of about 2,573,895 (298)
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Application of the consciousness index (IoC1) combined with injury sensitive index (IoC2) in cesarean section under general anesthesia [PDF]
Jichu yixue yu linchuang, 2021 Objective To investigate the application of the consciousness index 1(IoC1) combined with injury sensitive index 2(IoC2) in cesarean section under general anesthesia.
YUAN Bao-hong, LIU Xiao-nan
doaj
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Derivative based sensitivity analysis of gamma index
Journal of Medical Physics, 2015 Originally developed as a tool for patient-specific quality assurance in advanced treatment delivery methods to compare between measured and calculated dose distributions, the gamma index (γ) concept was later extended to compare between any two dose ...
Biplab Sarkar, Anirudh Pradhan, T Ganesh
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Construction of index system for nursing sensitivity of prone position ventilation in ICU patients
Huli yanjiu, 2020 ObjectiveTo construct the index system for nursing sensitivity of prone position ventilation in ICU patients based on the Donabedian model,so as to provide theoretical basis for evaluating the nursing quality of prone position ventilation.MethodsGuided ...
LANG Zijia, WANG Liping
doaj
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Indexicals, context-sensitivity and the failure of implication
Synthese, 2010 This paper investigates, formulates and proves an indexical barrier theorem, according to which sets of non-indexical sentences do not entail (except under specified special circumstances) indexical sentences. It surveys the usual difficulties for this kind of project, as well some that are specific to the case of indexicals, and adapts the strategy of
openaire +3 more sources