Results 101 to 110 of about 789,696 (298)
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
PLoS ONE, 2010 BackgroundSensitivity and robustness are essential properties of circadian clock systems, enabling them to respond to the environment but resist noisy variations.
Treenut Saithong +2 more
doaj +1 more source
Diagnosis of \u3cem\u3eSchistosoma mansoni\u3c/em\u3e without the Stool: Comparison of Three Diagnostic Tests to Detect \u3cem\u3eSchiostosoma mansoni\u3c/em\u3e Infection from Filtered Urine in Zambia [PDF]
, 2013 Diagnosis for intestinal Schistosoma mansoni lacks sensitivity and is arduous to conduct. The standard diagnostic tests, Kato-Katz (KK) and circulating cathodic antigen (CCA) both lack sensitivity and with KK, require obtaining, transporting, and ...
Lodh, Nilanjan +3 more
core +1 more source
Model selection and sensitivity analysis for sequence pattern models
, 2008 In this article we propose a maximal a posteriori (MAP) criterion for model selection in the motif discovery problem and investigate conditions under which the MAP asymptotically gives a correct prediction of model size. We also investigate robustness of
Gupta, Mayetri
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Mach-Zehnder interferometry with interacting trapped Bose-Einstein condensates
, 2011 We theoretically analyze a Mach-Zehnder interferometer with trapped condensates, and find that it is surprisingly stable against the nonlinearity induced by inter-particle interactions.
A. S. Holevo +5 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Jurnal Nasional Teknik Elektro, 2015 voltage response robustness of generator excitation system is the ability of generator excitation system to muffle noise at high frequency, has rapid response to specific input and is able to eliminate disturbance during operation.
Heru Dibyo Laksono +3 more
doaj +1 more source
Sensitivity and robustness in MDS configurations for mixed-type data: a study of the economic crisis impact on socially vulnerable Spanish people [PDF]
Multidimensional scaling (MDS) techniques are initially proposed to produce pictorial representations of distance, dissimilarity or proximity data. Sensitivity and robustness assessment of multivariate methods is essential if inferences are to be drawn ...
Aurea Grané, Rosario Romera
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source