Results 221 to 230 of about 86,685,215 (261)
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A Sensitive and Precise Radioimmunoassay for Human Thyroid-Stimulating Hormone
The Journal of Clinical Endocrinology & Metabolism, 1975A high-sensitivity radioimmunoassay for human thyroid-stimulating hormone (hTSH) has been developed utilizing a highly specific rabbit antibody (developed by AFP) to hTSH with an affinity constant of 4.4 x 10(11) M-1. Optimal conditions which minimized both 125I-hTSH radiation damage and 125I dissociation included storage at -60 C in 0.25% albumin ...
A E, Pekary, J M, Hershman, A F, Parlow
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Clinical use of sensitive assays for thyroid-stimulating hormone
Journal of General Internal Medicine, 1996To review the optimal use of sensitive assays for thyroid-stimulating hormone (TSH) by clinicians.The available literature pertinent to the clinical application of sensitive TSH testing was identified through a systematic MEDLINE search and reviewed. Selection of materials for inclusion was based on clinical validity of the data and relevance to the ...
P A, Masters, R J, Simons
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Modulation of lymphoid cell sensitivity to interferon by thyroid hormones
Journal of Endocrinological Investigation, 1990The possibility of increasing the responsiveness of lymphoid cells to Interferon (IFN) was investigated by studying the effect of the in vitro preincubation of spleen cells from young mice with thyroid hormone prior to the administration of IFN on their Natural Killer (NK) activity.
M, Provinciali, N, Fabris
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Effect of Dose of Thyroid Hormone on the Sensitivity of the McKenzie Bioassay*
Endocrinology, 1974Florsheirn reported that large doses of thyroid hormone, when employed for suppression of intrinsic TSH in McKenzie assay mice, reduced the response of the animal to TSH or LATS. Accelerated radioiodine clearance was proposed for the mechanism of this reduction in the response.
Y, Shishiba, S, Yoshimura, T, Shimizu
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Functional sensitivity of seven automated thyroid stimulating hormone immunoassays
Clinica Chimica Acta, 2011Serum thyroid stimulating hormone (TSH) measurements are useful for detecting clinical and subclinical primary hypo- and hyperthyroidism in ambulatory patients. For diagnosis of hyperthyroidism, the functional sensitivity (FS) is an important performance criterion, and current guidelines recommend an FS of ≤0.02 m IU/l for "third" generation ...
William E, Owen +4 more
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Clinical Endocrinology, 1993
SummaryOBJECTIVE We wished to ascertain whether different phenotypic appearances in patients with altered cellular sensitivity to thyroid hormones were related to the type of altered intra‐cellular thyroid hormone effect.DESIGN Blood samples were obtained from two members of a family suffering from generalized thyroid hormone resistance (GTHR) for ...
J, Kvetny, J, Bollerslev
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SummaryOBJECTIVE We wished to ascertain whether different phenotypic appearances in patients with altered cellular sensitivity to thyroid hormones were related to the type of altered intra‐cellular thyroid hormone effect.DESIGN Blood samples were obtained from two members of a family suffering from generalized thyroid hormone resistance (GTHR) for ...
J, Kvetny, J, Bollerslev
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The Anatomical Record, 1986
AbstractThyroids from rat fetuses of different ages (from day 14 to day 19 of gestation) were transplanted to organ culture for 2 days, with or without added thyroid‐stimulating hormone (TSH) in the medium. Thyroid tissue from 14‐day fetuses that initially consisted of irregularly arranged cell cords did not form follicles when cultured in the presence
M, Yamamoto +3 more
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AbstractThyroids from rat fetuses of different ages (from day 14 to day 19 of gestation) were transplanted to organ culture for 2 days, with or without added thyroid‐stimulating hormone (TSH) in the medium. Thyroid tissue from 14‐day fetuses that initially consisted of irregularly arranged cell cords did not form follicles when cultured in the presence
M, Yamamoto +3 more
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Journal of the American Geriatrics Society, 1989
The use of a screening test for thyroid functional disorder by sensitive thyroid stimulating hormone assay in the elderly was investigated. The basal thyroid stimulating hormone levels predicted the response of thyroid stimulating hormone to thyrotropin releasing hormone; it was suppressed in 99 (99.0%) of 100 hyperthyroid patients. Therefore, not only
K, Okamura +7 more
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The use of a screening test for thyroid functional disorder by sensitive thyroid stimulating hormone assay in the elderly was investigated. The basal thyroid stimulating hormone levels predicted the response of thyroid stimulating hormone to thyrotropin releasing hormone; it was suppressed in 99 (99.0%) of 100 hyperthyroid patients. Therefore, not only
K, Okamura +7 more
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Simple and sensitive test for thyroid hormone autoantibodies.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1997We presented a simple and sensitive test for thyroid hormone autoantibodies. The normal range for T4 and T3 autoantibodies in Thai people considering mean +/- 3 S.D. were 1.8-9.4 per cent and 3.1-8.6 per cent, respectively. Although positive low titer of thyroid hormone autoantibodies had almost no interference of thyroid hormone levels, high titer ...
T, Sunthornthepvarakul +6 more
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Periods of Sensitivity to Thyroid Hormone during the Development of the Organ of Corti
Acta Oto-Laryngologica, 1986Cochlear structures are sensitive to the morphogenetic effect of thyroid hormone during the whole duration of maturation. For each structure, there exists a period of maximal sensitivity to thyroid hormone which corresponds to the period of development during which the structure of interest undergoes its main morphological changes (6 to 13 days for the
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